SCHEMBL6746972

SCHEMBL6746972

CC(C)(C)[Si](C)(C)OCc1csc(C=O)c1CO[Si](C)(C)C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6748783 0.78 BACE1 (0.38) BACE1
SCHEMBL6748908 0.75 BACE1 (0.35) BACE1
SCHEMBL30219107 0.71 BACE1 (0.56) BACE1
SCHEMBL2082920 0.71 BACE1 (0.56) BACE1
SCHEMBL3134778 0.71 BACE1 (0.32) BACE1
SCHEMBL17410684 0.70 BACE1 (0.33) BACE1
SCHEMBL31169393 0.70 CA2 (0.32) BACE1
SCHEMBL17410311 0.69 USP14 (0.31) BACE1
SCHEMBL3125945 0.69 BACE1 (0.30) BACE1
SCHEMBL13486790 0.68 SRC (0.36) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6703373-B1 ANTICARCINOGENIC AGENTS BANYU PHARMACEUTICAL CO., LTD. (JP) 2004-03-09 US disclosed