Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743703 | 0.91 | PTGS2 (0.52) | PTGS2PTGS1SCN9A | |
| SCHEMBL6746755 | 0.90 | SCN9A (0.44) | PTGS2PTGS1SCN9A | |
| SCHEMBL6743648 | 0.89 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL6746028 | 0.89 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6746854 | 0.86 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6744855 | 0.86 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL6750053 | 0.86 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL6745443 | 0.85 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL6744141 | 0.85 | PTGS2 (0.40) | PTGS2 | |
| SCHEMBL6745224 | 0.84 | NR1H2 (0.40) | PTGS2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |