Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | FEN1 | P39748 | 5/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750040 | 0.89 | PTGS2 (0.46) | PTGS2FEN1ALOX5APCA1CA2 | |
| SCHEMBL6750085 | 0.86 | ALOX5AP (0.39) | PTGS2FEN1ALOX5APCA1CA2 | |
| SCHEMBL6721421 | 0.85 | PTGS2 (0.52) | PTGS2FEN1ALOX5APCA1CA2 | |
| SCHEMBL6747071 | 0.85 | FEN1 (0.44) | FEN1ALOX5APCA1CA2CA9 | |
| SCHEMBL6749919 | 0.85 | PTGS2 (0.47) | PTGS2FEN1ALOX5APCA1CA2 | |
| SCHEMBL6746459 | 0.85 | CA1 (0.40) | FEN1ALOX5APCA1CA2CA9 | |
| SCHEMBL6749461 | 0.84 | FEN1 (0.47) | PTGS2FEN1ALOX5APCA1CA2 | |
| SCHEMBL6746036 | 0.83 | FEN1 (0.40) | FEN1ALOX5APCA1CA2CA9 | |
| SCHEMBL6743644 | 0.83 | NPC1 (0.44) | PTGS2FEN1ALOX5APCA1CA2 | |
| SCHEMBL6744800 | 0.83 | FEN1 (0.40) | PTGS2FEN1ALOX5APCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |