Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.58 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22063715 | 0.79 | ASIC3 (0.56) | ASIC3MIFKMOKMT2ANPC1 | |
| SCHEMBL284286 | 0.79 | ASIC3 (0.71) | ASIC3MIFKMOKMT2ANPC1 | |
| SCHEMBL28218682 | 0.77 | ASIC3 (0.68) | ASIC3MIFKMOKMT2ANPC1 | |
| SCHEMBL27904874 | 0.77 | ASIC3 (0.68) | ASIC3MIFKMOKMT2ANPC1 | |
| SCHEMBL29406194 | 0.77 | ASIC3 (0.68) | ASIC3MIFKMOKMT2ANPC1 | |
| SCHEMBL29730373 | 0.74 | ASIC3 (0.65) | ASIC3MIFKMOKMT2ANPC1 | |
| SCHEMBL17697185 | 0.74 | ASIC3 (0.65) | ASIC3MIFKMOKMT2ANPC1 | |
| SCHEMBL18731738 | 0.74 | ASIC3 (0.65) | ASIC3MIFKMOKMT2ANPC1 | |
| SCHEMBL30412356 | 0.74 | ASIC3 (0.59) | ASIC3MIFKMOKMT2ANPC1 | |
| SCHEMBL2129077 | 0.74 | ASIC3 (0.59) | ASIC3MIFKMOKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777412-B2 | PYRIMIDIN-4-YLOXY)PHENYL)-3-METHOXYPROPENOATE DERIVATIVES | SYNGENTA LIMITED (GB) | 2004-08-17 | — | — | US | disclosed |
| US-20040092746-A1 | Pyrimidinyloxyphenyl-3-alkoxypropenoate derivatives as pesticides | CLOUGH JOHN MARTIN (GB) | 2004-05-13 | — | — | US | disclosed |
| US-6613773-B2 | Pyrimidinyloxyphenyl-3-alkoxypropenoates derivatives | SYNGENTA LIMITED (GB) | 2003-09-02 | — | — | US | disclosed |
| US-20030060626-A1 | Fungicides | SYNGENTA LIMITED (GB) | 2003-03-27 | — | — | US | disclosed |
| CN-1036519-C | Fungicides | ICI PLC (GB) | 1997-11-26 | — | — | CN | disclosed |
| EP-0468695-B1 | Fungicides | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| EP-0468695-A1 | Fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092746-A1 | Pyrimidinyloxyphenyl-3-alkoxypropenoate derivatives as pesticides | DDT, SQOR, TH | ASIC3 972/4885MIF 4028/4885KMO 37/4885 |
| US-20030060626-A1 | Fungicides | CYP51A1, CYP1A1, CYP1A2 | ASIC3 2231/4885MIF 3360/4885KMO 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.