Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | HTT | P42858 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13102388 | 0.87 | ALDH1A1 (0.61) | ALDH1A1HTTKMT2ALMNAMEN1 | |
| SCHEMBL13101672 | 0.86 | ALDH1A1 (0.79) | ALDH1A1HTTKMT2ALMNAMEN1 | |
| SCHEMBL13102204 | 0.85 | ALDH1A1 (0.61) | ALDH1A1HTTKMT2ALMNAMEN1 | |
| SCHEMBL13101609 | 0.85 | LMNA (0.62) | ALDH1A1HTTKMT2ALMNAMEN1 | |
| SCHEMBL13255259 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HTTKMT2ALMNAMEN1 | |
| SCHEMBL13101642 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTKMT2ALMNAMEN1 | |
| SCHEMBL13101731 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HTTKMT2ALMNAMEN1 | |
| SCHEMBL13101974 | 0.82 | NPSR1 (0.59) | ALDH1A1HTTKMT2ALMNAMEN1 | |
| SCHEMBL30794826 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HTTKMT2ALMNAMEN1 | |
| SCHEMBL2751773 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HTTKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178544-B2 | 2, 3-diamino-quinazolinone derivatives and their medical use | NEUROSEARCH A/S (DK) | 2012-05-15 | — | — | US | disclosed |
| US-20100160315-A1 | NOVEL 2, 3-DIAMINO-QUINAZOLINONE DERIVATIVES AND THEIR MEDICAL USE | NEURO SEARCH A/S (DK) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160315-A1 | NOVEL 2, 3-DIAMINO-QUINAZOLINONE DERIVATIVES AND THEIR MEDICAL USE | KCNJ2, KCNN3, KCNK17 | ALDH1A1 1660/4885HTT 893/4885KMT2A 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.