Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744423 | 0.97 | CYP2A6 (0.68) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6743757 | 0.82 | KDM4E (0.60) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6747700 | 0.79 | CYP2A6 (0.54) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6654002 | 0.79 | KDM4E (0.52) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 | |
| [2,3'']Bipyridinyl SCHEMBL29360744 | 0.79 | CYP2A6 (1.00) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 | |
| [2,3'']Bipyridinyl SCHEMBL29486847 | 0.79 | CYP2A6 (1.00) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 | |
| [2,3'']Bipyridinyl SCHEMBL29389597 | 0.79 | CYP2A6 (1.00) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 | |
| [2,3'']Bipyridinyl SCHEMBL998601 | 0.79 | CYP2A6 (1.00) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL6744236 | 0.78 | KDM4E (0.50) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 | |
| [2,3'']Bipyridinyl SCHEMBL1418333 | 0.77 | CYP2A6 (0.96) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696182-B2 | HIGH PERFORMANCE DIPYRIDYL THIOPHENE OR DIPYRIDYL THIOPHENE DIOXIDE ELECTRON TRANSPORT MATERIALS WHICH WHEN EMPLOYED CAN GIVE LOW-VOLTAGE, HIGH EFFICIENCY ORGANIC ELECTROLUMINESCENT DEVICES | CHISSO CORPORATION (JP) | 2004-02-24 | — | — | US | disclosed |
| EP-1186605-B1 | Organic electroluminescent device comprising dipyridylthiophene derivative | CHISSO CORP (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-20020034658-A1 | Organic electroluminescent device comprising dipyridylthiophene derivative | CHISSO CORPORATION (JP) | 2002-03-21 | — | — | US | disclosed |
| EP-1186605-A1 | Organic electroluminescent device comprising dipyridylthiophene derivative | CHISSO CORPORATION (JP) | 2002-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020034658-A1 | Organic electroluminescent device comprising dipyridylthiophene derivative | LAGE3, MAL2, ELF3 | CYP2A6 3732/4885NPC1 4465/4885RAB9A 3876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.