SCHEMBL6748007

SCHEMBL6748007

COc1ncnc(C)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2654847 0.84 MEN1 (0.40)
SCHEMBL9853166 0.82 GAA (0.37)
SCHEMBL467436 0.74
SCHEMBL2595268 0.73
SCHEMBL11212319 0.73
SCHEMBL10879846 0.73
SCHEMBL16511790 0.73
SCHEMBL14644320 0.73
SCHEMBL19050223 0.70 ALDH1A1 (0.33)
SCHEMBL9853047 0.70 CRHR1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1558898-A Antiviral agent ��Ұ����ҩ��ʽ���� 2004-12-29 CN claimed
US-20220048890-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2022-02-17 US disclosed
CN-113372283-B Synthetic method of 2-methylamino-4-methoxy-6-methyl-1, 3, 5-triazine 南京合创药业有限公司 2021-11-05 CN disclosed
CN-113372283-A Synthetic method of 2-methylamino-4-methoxy-6-methyl-1, 3, 5-triazine 南京合创药业有限公司 2021-09-10 CN disclosed
US-11041084-B2 Finishing method for reactive dye inkjet printing based on the cationic modifier ink DONGHUA UNIVERSITY (CN) 2021-06-22 US disclosed
US-20200317943-A1 FINISHING METHOD FOR REACTIVE DYE INKJET PRINTING BASED ON THE CATIONIC MODIFIER INK DONGHUA UNIVERSITY (CN) 2020-10-08 US disclosed
US-20170183348-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2017-06-29 US disclosed
US-9629836-B2 Compounds and compositions as inhibitors of MEK NOVARTIS AG (CH) 2017-04-25 US disclosed
US-20160264614-A1 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2016-09-15 US disclosed
US-20160136150-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK NOVARTIS AG (CH) 2016-05-19 US disclosed
US-20130184248-A1 NOVEL COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-07-18 US disclosed
CN-100491349-C Antiviral agent SHIONOGI & CO (JP) 2009-05-27 CN disclosed
CN-1558898-A Antiviral agent ��Ұ����ҩ��ʽ���� 2004-12-29 CN disclosed
US-6699654-B1 USING INHIBITORS OF PLANT-LIKE METABOLIC PATHWAYS (NOT ASSOCIATED WITH ANIMALS, NOT ENCODED IN THE PLASTID GENOME, NOT INCLUDING PSBA OR PPI PHOSPHOFRUCTOKINASE) TO DEVELOP THE PARASITICIDE; GABACULINE AND SULFADIAZINE MRJ TRUST C/O MARK E. RUST 2004-03-02 US disclosed
EP-0987945-B1 NEW HERBICIDAL MIXTURES AVENTIS CROPSCIENCE SA (FR) 2001-10-24 EP disclosed
US-6239070-B1 REDUCING PHYTOTOXICITY USING 4-BENZOYLISOXAZOLE HERBICIDE;MIXTURE CONTAINING PLANT SAFENING AGENT RHONE-POULENC INC. 2001-05-29 US disclosed
US-6150301-A Chemical abscission of fruits at low application rates WILCOX MERRILL (US) 2000-11-21 US disclosed
EP-0987945-A1 NEW HERBICIDAL MIXTURES RHONE-POULENC AGROCHIMIE (FR) 2000-03-29 EP disclosed
WO-1998056251-A1 NEW HERBICIDAL MIXTURES RHONE-POULENC AGRO (FR) 1998-12-17 WO disclosed
EP-0356828-A2 Process for the preparation of sulfonyl isothiourea BAYER AG (DE) 1990-03-07 EP disclosed