SCHEMBL2654847

SCHEMBL2654847

COc1ncnc(OC)n1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
CYP1A2 P05177 2/20 0.35
MAPT P10636 1/20 0.34
TSHR P16473 1/20 0.34
ATM Q13315 1/20 0.34
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PDPK1 O15530 1/20 0.32
EGFR P00533 1/20 0.32
FTO Q9C0B1 1/20 0.31
PIK3CA P42336 1/20 0.31
MTOR P42345 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6748007 0.84
SCHEMBL10879846 0.82
SCHEMBL16511790 0.82
SCHEMBL2595268 0.82
SCHEMBL11212319 0.82
SCHEMBL9597493 0.82 LMNA (0.32) MEN1KMT2AALDH1A1MAPTLMNA
Piperidine SCHEMBL20639960 0.80 ALDH1A1 (0.36) MEN1KMT2AALDH1A1CYP1A2ATM
SCHEMBL3782708 0.78
SCHEMBL9853047 0.78 CRHR1 (0.30)
SCHEMBL19050223 0.78 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2EGFRPIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099144-A1 SELF-CROSSLINKED HYDROGEL COMBINATION WITH BOTULINUM NEUROTOXIN MERZ PHARMA GMBH & CO. KGAA (DE) 2026-05-15 WO claimed
CN-121574104-A Preparation method, condensing agent and application of cosmetic peptide prolyl-lysine 天津卡普希科技有限公司 2026-02-27 CN claimed
CN-114989155-B 1,3, 4-oxadiazole thioether derivative, and preparation method and application thereof 河北农业大学 2024-04-02 CN claimed
CN-117500535-A Cross-linking polysaccharides with fibroin and use of the obtained material 莫茨制药有限及两合公司 2024-02-02 CN claimed
CN-114989155-A 1,3, 4-oxadiazole thioether derivative and preparation method and application thereof 河北农业大学 2022-09-02 CN claimed
CN-110016041-A A kind of Stemona alkaloids analog and preparation method and purposes 山西大学 2019-07-16 CN claimed
CN-109627599-A A kind of graphene Electric radiant Heating Film flame-retardant polypropylene film hermetic bag 福建久信科技有限公司 2019-04-16 CN claimed
CN-108349985-A Solid forms of isoquinolinones, methods of making, compositions containing, and methods of use thereof 无限药品股份有限公司 2018-07-31 CN claimed
CN-105531276-A Method for preparing improved intermediate for preparing high purity pemetrexed and method for preparing high purity pemetrexed using the same SAMYANG BIOPHARMACEUTICALS 2016-04-27 CN claimed
CN-104910086-A Preparation method of 2-chloro-4,6-dimethoxy-1,3,5-triazine ANHUI SHINDO CHEMICAL CO LTD 2015-09-16 CN claimed
CN-102256614-A Synthetic mimetics of host defense and uses thereof POLYMEDIX INC 2011-11-23 CN claimed
CN-101624379-B Method for preparing 2-chlorine-4, 6-dimethoxy-1, 3, 5-triazine SUZHOU TIME CHEM TECHNOLOGIES CO LTD 2011-04-27 CN claimed
CN-101824012-A 2-(1,6,7,8-tetrahydrogen-2H-indeno-[5,4-b] furan-8-group) acetonitrile, preparation method and applciation UNIV SICHUAN 2010-09-08 CN claimed
CN-101624379-A Method for preparing 2-chlorine-4, 6-dimethoxy-1, 3, 5-triazine SUZHOU TIME CHEM TECHNOLOGIES 2010-01-13 CN claimed
CN-101034260-A Photosensitive resin composition DONGJIN SEMICHEM CO LTD (KR) 2007-09-12 CN claimed
CN-1546476-A Preparation method of 2-methyl-4-methylamino-6-methoxy-1, 3, 5-triazine �Ͼ���ҵ��ѧ 2004-11-17 CN claimed
US-20030209491-A1 Simulated activity of protein a displayed by ligands attached to a cellulose bead surface ACCURATE POLYMERS, LTD. 2003-11-13 US claimed
EP-1276557-A2 SIMULATED ACTIVITY OF PROTEIN A DISPLAYED BY LIGANDS ATTACHED TO A CELLULOSE BEAD SURFACE Accurate Polymers, Ltd. (US) 2003-01-22 EP claimed
US-20010045384-A1 Simulated activity of protein a displayed by ligands attached to a cellulose bead surface ACCURATE POLYMERS, LTD. 2001-11-29 US claimed
WO-2001083515-A2 SIMULATED ACTIVITY OF PROTEIN A DISPLAYED BY LIGANDS ATTACHED TO A CELLULOSE BEAD SURFACE ACCURATE POLYMERS, INC. (US) 2001-11-08 WO claimed