SCHEMBL674816

SCHEMBL674816

CCCCCc1cccc(Sc2cccc(CCCCC)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.54
LIPG Q9Y5X9 3/20 0.54
HTR2C P28335 1/20 0.53
HTR6 P50406 1/20 0.53
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PPARG P37231 3/20 0.45
PPARA Q07869 3/20 0.45
CYP3A4 P08684 1/20 0.42
PTGS2 P35354 1/20 0.42
KCNH2 Q12809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10610847 0.98 LPL (0.56) LPLLIPGHTR2CHTR6TDP1
SCHEMBL10448781 0.96 LPL (0.54) LPLLIPGHTR2CHTR6TDP1
SCHEMBL18395319 0.85 LPL (0.54) LPLLIPGTDP1L3MBTL1PPARG
SCHEMBL12040880 0.85 LPL (0.54) LPLLIPGTDP1L3MBTL1PPARG
SCHEMBL8518305 0.83 LPL (0.66) LPLLIPGHTR2CTDP1L3MBTL1
SCHEMBL11767642 0.83 LPL (0.42) LPLLIPGHTR2CHTR6PPARG
SCHEMBL5249436 0.81 LPL (0.67) LPLLIPGHTR2CPPARGPPARA
SCHEMBL6932623 0.81 LPL (0.67) LPLLIPGHTR2CPPARGPPARA
SCHEMBL4032533 0.81 LPL (0.67) LPLLIPGHTR2CPPARGPPARA
SCHEMBL9420947 0.81 LPL (0.63) LPLLIPGHTR2CTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2174547-B1 PEST CONTROL AGENT COMPOSITION AND PEST CONTROLLING METHOD KUMIAI CHEMICAL INDUSTRY CO (JP) 2017-01-18 EP claimed
US-20110067612-A1 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PEST KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2011-03-24 US claimed
US-7767626-B2 3-arylphenyl sulfide derivative and insecticide and miticide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-08-03 US claimed
EP-2174547-A1 PEST CONTROL AGENT COMPOSITION AND PEST CONTROLLING METHOD Kumiai Chemical Industry CO., LTD. (JP) 2010-04-14 EP claimed
US-20090170883-A1 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-07-02 US claimed
EP-1076053-B1 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 2006-11-29 EP claimed
US-7037930-B2 3-arylphenyl sulfide derivative and insecticide and miticide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2006-05-02 US claimed
US-20050171097-A1 3-Arylphenyl sulfide derivative and insecticide and miticide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-08-04 US claimed
US-20050107383-A1 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-05-19 US claimed
US-6858639-B2 3-Arylphenyl sulfide derivative and insecticide and miticide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-02-22 US claimed
US-20030069242-A1 3-arylphenyl sulfide derivative and insecticide and miticide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2003-04-10 US claimed
US-6509354-B1 Insecticides and miticides containing the 3-arylphenyl sulfide derivatives as an active ingredient. KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2003-01-21 US claimed
EP-1076053-A1 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2001-02-14 EP claimed
EP-3483144-B1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD CONTROLLING AGENT CONTAINING SAME SUMITOMO CHEMICAL CO (JP) 2023-10-11 EP disclosed
EP-2865671-B1 FUSED HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-11-01 EP disclosed
EP-2174547-B1 PEST CONTROL AGENT COMPOSITION AND PEST CONTROLLING METHOD KUMIAI CHEMICAL INDUSTRY CO (JP) 2017-01-18 EP disclosed
US-6509354-B1 Insecticides and miticides containing the 3-arylphenyl sulfide derivatives as an active ingredient. KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2003-01-21 US disclosed
EP-1076053-A1 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2001-02-14 EP disclosed
EP-1076053-A1 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2001-02-14 EP disclosed
WO-1999055668-A1 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1999-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170883-A1 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE CBR3, MSRB3, CYP1B1 LPL 2309/4885LIPG 4684/4885HTR2C 177/4885
US-20030069242-A1 3-arylphenyl sulfide derivative and insecticide and miticide CYP1B1, CYP2B6, CBR3 LPL 1354/4885LIPG 4430/4885HTR2C 107/4885
US-20050171097-A1 3-Arylphenyl sulfide derivative and insecticide and miticide CBR3, MSRB3, CYP1B1 LPL 2309/4885LIPG 4684/4885HTR2C 177/4885
US-20110067612-A1 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PEST TRHDE, DDT, AADAC LPL 3323/4885LIPG 3952/4885HTR2C 416/4885
US-20050107383-A1 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE CBR3, MSRB3, CYP1B1 LPL 2309/4885LIPG 4684/4885HTR2C 177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.