SCHEMBL674818

SCHEMBL674818

OP(Oc1cccc2ccccc12)Oc1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 3/20 0.47
HPGD P15428 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HSD17B10 Q99714 3/20 0.46
PGR P06401 1/20 0.46
GAA P10253 1/20 0.46
PTGS1 P23219 1/20 0.46
MAPK1 P28482 1/20 0.46
HTR1B P28222 5/20 0.46
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
CYP1A2 P05177 2/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP2C19 P33261 1/20 0.44
NR2E1 Q9Y466 1/20 0.43
KCNA3 P22001 1/20 0.43
HTR1D P28221 2/20 0.42
OGG1 O15527 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7125289 0.91 KCNA3 (0.49) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL10619494 0.88 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL8385831 0.88 HTR1B (0.44) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL6057475 0.87 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL28365939 0.84 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL28783442 0.84 KCNA3 (0.46) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL31556331 0.82 HTR1B (0.48) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL1449787 0.82 HTR1B (0.48) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL1604278 0.79 HTR1B (0.43) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL7939035 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDTDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946169-A Axis chiral binaphthyl phosphite skeleton tridentate P, N, N-ligand, preparation method and application thereof 中国科学院大连化学物理研究所 2024-04-30 CN claimed
CN-110483569-B Polycarbonate antioxidant, preparation method and polycarbonate composition 万华化学集团股份有限公司 2022-02-18 CN claimed
CN-110483569-A A kind of polycarbonate antioxidant, preparation method and a kind of polycarbonate compositions WANHUA CHEMICAL GROUP CO LTD 2019-11-22 CN claimed
US-8193274-B2 Metal-clad laminates having improved peel strength and compositions useful for the preparation thereof ARLON (US) 2012-06-05 US claimed
WO-2009088653-A1 METAL-CLAD LAMINATES HAVING IMPROVED PEEL STRENGTH AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF ARLON (US) 2009-07-16 WO claimed
US-20090176106-A1 METAL-CLAD LAMINATES HAVING IMPROVED PEEL STRENGTH AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF ARLON 2009-07-09 US claimed
CN-119219696-A Phosphine-containing polycarbonate high-temperature degradation resistant agent, preparation method and polycarbonate composition 万华化学集团股份有限公司 2024-12-31 CN disclosed
CN-117946169-A Axis chiral binaphthyl phosphite skeleton tridentate P, N, N-ligand, preparation method and application thereof 中国科学院大连化学物理研究所 2024-04-30 CN disclosed
CN-117946169-A Axis chiral binaphthyl phosphite skeleton tridentate P, N, N-ligand, preparation method and application thereof 中国科学院大连化学物理研究所 2024-04-30 CN disclosed
CN-117946169-A Axis chiral binaphthyl phosphite skeleton tridentate P, N, N-ligand, preparation method and application thereof 中国科学院大连化学物理研究所 2024-04-30 CN disclosed
EP-3647387-B1 CURABLE EPOXIDE COMPOSITION T&K TOKA CO LTD (JP) 2023-06-28 EP disclosed
US-20230159743-A1 HEAT-CURABLE EPOXY RESIN COMPOSITION AND HEAT-CURABLE EPOXY RESIN SHEET SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
CN-112142583-B Method for preparing neral from geranial 万华化学集团股份有限公司 2022-07-26 CN disclosed
US-4181642-A Process for the production of a glycidyl group containing acrylic resin and its use DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-01-01 US disclosed
US-4110306-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, a triphosphite, and an acid phosphite or salt thereof ARGUS CHEMICAL CORPORATION (US) 1978-08-29 US disclosed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4104050-A Acetimidic (α-diaryloxyphosphinylmethylamino) acid ester hydrochlorides, herbicidal composition and herbicidal use thereof MONSANTO COMPANY (US) 1978-08-01 US disclosed
US-4080364-A Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures ARGUS CHEMICAL CORPORATION (US) 1978-03-21 US disclosed
US-4067903-A Manufacture of arylamines BASF AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed
US-3997551-A OXIDATION RESISTANCE, STABILIZE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1976-12-14 US disclosed