SCHEMBL7939035

SCHEMBL7939035

O=[P](Oc1cccc2ccccc12)Oc1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HSD17B10 Q99714 3/20 0.46
PGR P06401 1/20 0.46
GAA P10253 1/20 0.46
PTGS1 P23219 1/20 0.46
MAPK1 P28482 1/20 0.46
HTR1B P28222 5/20 0.46
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KCNA3 P22001 1/20 0.43
OGG1 O15527 1/20 0.42
HTR1D P28221 1/20 0.42
FABP7 O15540 3/20 0.41
FABP3 P05413 3/20 0.41
FABP5 Q01469 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23440626 0.86 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL31556331 0.82 HTR1B (0.48) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL1449787 0.82 HTR1B (0.48) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL9328235 0.78 HTR1B (0.46) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL6057475 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL5960896 0.78 HTR1B (0.46) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL674818 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL8385831 0.76 HTR1B (0.44) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL11706817 0.75 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL9328250 0.75 HTR1B (0.43) ALDH1A1KDM4EHPGDTDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1082285-A1 HYDROFORMYLATION OF OLEFINS USING SUPPORTED BIS(PHOSPHORUS) LIGANDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-03-14 EP disclosed
EP-1003607-A2 SUPPORTED DIOLS AND SUPPORTED BIS(PHOSPHORUS) LIGANDS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2000-05-31 EP disclosed
WO-1999062855-A1 HYDROFORMYLATION OF OLEFINS USING SUPPORTED BIS(PHOSPHORUS) LIGANDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-12-09 WO disclosed
WO-1999006146-A2 SUPPORTED DIOLS AND SUPPORTED BIS(PHOSPHORUS) LIGANDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-11 WO disclosed
EP-0090366-B1 1-AZABICYCLO(3.2.0)HEPT-2-ENE-2-CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-11-25 EP disclosed
US-4640915-A MICROBIOCIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-02-03 US disclosed
EP-0012397-B1 POLYMERIZATION CATALYST AND PROCESS FOR POLYMERIZING ALPHA-OLEFINS PHILLIPS PETROLEUM COMPANY (US) 1984-02-15 EP disclosed
EP-0090366-A1 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-10-05 EP disclosed