Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 8/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GCG | P01275 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751919 | 0.86 | MCHR1 (0.44) | GCGRMCHR1PPARDPPARGPPARA | |
| SCHEMBL6751722 | 0.86 | GCG (0.38) | GCGRGCGNPSR1 | |
| SCHEMBL6754062 | 0.84 | GCGR (0.40) | GCGRGCG | |
| SCHEMBL6748286 | 0.83 | MCHR1 (0.42) | GCGRMCHR1PPARDPPARGPPARA | |
| SCHEMBL6905471 | 0.78 | OPRM1 (0.40) | GCGRPPARDGCGCYP2D6OPRM1 | |
| SCHEMBL2650299 | 0.77 | GCGR (0.40) | GCGRPPARDGCGCYP2D6OPRM1 | |
| SCHEMBL6753873 | 0.77 | ALDH1A1 (0.43) | GCGRGCGCYP2D6NPSR1OPRM1 | |
| SCHEMBL6751922 | 0.77 | EPHX2 (0.42) | GCGRMCHR1GCGCYP2D6NPSR1 | |
| SCHEMBL2661429 | 0.77 | ALDH1A1 (0.41) | GCGRGCGCYP2D6NPSR1OPRM1 | |
| SCHEMBL9071467 | 0.76 | GCGR (0.51) | GCGRMCHR1PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706744-B2 | HYPOGLYCEMIC AGENTS; ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2004-03-16 | — | — | US | claimed |