Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748927 | 0.80 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL6748928 | 0.80 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL6750481 | 0.72 | PAOX (0.45) | MAPTALDH1A1 | |
| SCHEMBL211717 | 0.71 | CES2 (0.41) | ALDH1A1HSD17B10 | |
| SCHEMBL214835 | 0.71 | CES2 (0.41) | ALDH1A1HSD17B10 | |
| SCHEMBL214834 | 0.71 | CES2 (0.41) | ALDH1A1HSD17B10 | |
| SCHEMBL211718 | 0.71 | CES2 (0.41) | ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9052073 | 0.70 | CES2 (0.39) | ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9052071 | 0.70 | CES2 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL3691413 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233669-B1 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2004-02-25 | — | — | EP | claimed |
| EP-1233669-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-08-28 | — | — | EP | claimed |
| US-6365549-B2 | PRESERVATION | NORTH CAROLINA STATE UNIVERSITY | 2002-04-02 | — | — | US | claimed |
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | NORTH CAROLINA STATE UNIVERSITY | 2001-09-06 | — | — | US | claimed |
| WO-2001037663-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-05-31 | — | — | WO | claimed |
| EP-1233669-B1 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2004-02-25 | — | — | EP | disclosed |
| EP-1233669-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6365549-B2 | PRESERVATION | NORTH CAROLINA STATE UNIVERSITY | 2002-04-02 | — | — | US | disclosed |
| WO-2001037663-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | PRUNE1, NOTUM, FAR1 | MAPT 4725/4885CYP2D6 4193/4885ALDH1A1 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.