SCHEMBL6748520

SCHEMBL6748520

CCO[Si](C)(C)c1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(N(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 1/20 0.33
ENPP3 O14638 2/20 0.33
ENPP1 P22413 2/20 0.33
TSHR P16473 2/20 0.32
ALDH1A1 P00352 2/20 0.32
RAB9A P51151 4/20 0.31
NPC1 O15118 3/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KMT2A Q03164 1/20 0.30
TRPM8 Q7Z2W7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6749512 0.95 ALDH1A1 (0.35) TSHRALDH1A1RAB9APOLBKMT2A
SCHEMBL6746764 0.95 ALDH1A1 (0.35) TSHRALDH1A1RAB9APOLBKMT2A
SCHEMBL6751493 0.94 RAB9A (0.36) TARBP2ENPP3ENPP1ALDH1A1RAB9A
SCHEMBL6746802 0.94 RAB9A (0.36) TARBP2ENPP3ENPP1ALDH1A1RAB9A
SCHEMBL6751494 0.94 RAB9A (0.36) TARBP2ENPP3ENPP1ALDH1A1RAB9A
SCHEMBL6745153 0.94 RAB9A (0.36) TARBP2ENPP3ENPP1ALDH1A1RAB9A
SCHEMBL6751424 0.89 CNR2 (0.31)
SCHEMBL6745055 0.89 CYP2C19 (0.39) TSHRALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL6745103 0.89 CYP2C19 (0.39) TSHRALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL6746704 0.89 CYP2C19 (0.39) TSHRALDH1A1RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696588-B2 OXIDATION POTENTIAL OF .3-1.5 V ON THE BASIS OF A STANDARD HYDROGEN ELECTRODE, ALKOXY AND AROMATIC AMINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-02-24 US disclosed
EP-0861845-B1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL CO (JP) 2003-05-28 EP disclosed
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-08-22 US disclosed
US-6369258-B1 SILICON COMPOUND WITH OXIDATION POTENTIAL ON HYDROGEN ELECTRODE POTENTIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-09 US disclosed
EP-0861845-A2 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same EPCAM, PIEZO1, OR10J3 TARBP2 2848/4885ENPP3 2689/4885ENPP1 3167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.