SCHEMBL6748919

SCHEMBL6748919

CCOCc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.59
HTT P42858 4/20 0.59
MAPT P10636 3/20 0.59
RAB9A P51151 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
GAA P10253 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.58
ATM Q13315 1/20 0.58
ELANE P08246 2/20 0.51
PPARG P37231 2/20 0.51
HPGD P15428 4/20 0.51
NPSR1 Q6W5P4 2/20 0.51
PPARA Q07869 1/20 0.51
SRD5A2 P31213 3/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HSP90AB1 P08238 1/20 0.50
FNTA P49354 1/20 0.48
FNTB P49356 1/20 0.48
LMNA P02545 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4711414 0.89 ALDH1A1 (0.60) ALDH1A1HTTMAPTRAB9ASMN1; SMN2
SCHEMBL12110127 0.85 ALDH1A1 (0.57) ALDH1A1HTTMAPTRAB9ASMN1; SMN2
Benzophenone SCHEMBL9809029 0.85 ALDH1A1 (0.64) ALDH1A1HTTMAPTRAB9ASMN1; SMN2
Benzophenone SCHEMBL1147390 0.85 ALDH1A1 (0.64) ALDH1A1HTTMAPTRAB9ASMN1; SMN2
Benzophenone SCHEMBL1147611 0.85 ALDH1A1 (0.64) ALDH1A1HTTMAPTRAB9ASMN1; SMN2
SCHEMBL28440984 0.84 RAB9A (0.63) ALDH1A1HTTMAPTRAB9ASMN1; SMN2
SCHEMBL1749635 0.83 ALDH1A1 (0.61) ALDH1A1RAB9ASMN1; SMN2
SCHEMBL5965867 0.83 ALDH1A1 (0.55) ALDH1A1HTTMAPTRAB9ASMN1; SMN2
Benzophenone SCHEMBL7925282 0.83 ALDH1A1 (0.61) ALDH1A1HTTMAPTRAB9ASMN1; SMN2
SCHEMBL11472200 0.81 ATM (0.66) ALDH1A1HTTMAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4199420-A ETHYLENICALLY UNSATURATED MONOMERS STAUFFER CHEMICAL COMPANY (US) 1980-04-22 US claimed
US-20240342347-A1 BIOFOULING RESISTANT COATINGS FOR MEDICAL DEVICES BANK OF MONTREAL, AS COLLATERAL AGENT 2024-10-17 US disclosed
US-6702851-B1 Prosthetic heart valve with surface modification CORCYM S.R.L. (IT) 2004-03-09 US disclosed
US-4199420-A ETHYLENICALLY UNSATURATED MONOMERS STAUFFER CHEMICAL COMPANY (US) 1980-04-22 US disclosed