Benzophenone

Benzophenone

SCHEMBL7925282

CCOCC.O=C(c1ccccc1)c1ccccc1.[NaH]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
ELANE P08246 2/20 0.55
HPGD P15428 4/20 0.53
L3MBTL1 Q9Y468 3/20 0.52
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
SRD5A2 P31213 1/20 0.52
RAB9A P51151 5/20 0.50
LMNA P02545 3/20 0.50
MAPK1 P28482 1/20 0.50
NPC1 O15118 1/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
GAA P10253 2/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL9809029 0.98 ALDH1A1 (0.64) ALDH1A1ELANEHPGDL3MBTL1ATM
Benzophenone SCHEMBL1147390 0.98 ALDH1A1 (0.64) ALDH1A1ELANEHPGDL3MBTL1ATM
Benzophenone SCHEMBL1147611 0.98 ALDH1A1 (0.64) ALDH1A1ELANEHPGDL3MBTL1ATM
Benzophenone SCHEMBL28105799 0.90 RAB9A (0.60) ALDH1A1ELANEHPGDL3MBTL1ATM
Benzoic Acid SCHEMBL931656 0.84 TSHR (0.64) ALDH1A1SRD5A2LMNANPC1MEN1
Benzil SCHEMBL2684477 0.84 CES2 (0.64) ALDH1A1HPGDRAB9ALMNACES2
Benzoic Acid SCHEMBL9460609 0.84 TSHR (0.64) ALDH1A1SRD5A2LMNANPC1MEN1
Benzophenone SCHEMBL8089683 0.84 ALDH1A1 (0.78) ALDH1A1ELANEHPGDL3MBTL1ATM
SCHEMBL6748919 0.83 ALDH1A1 (0.59) ALDH1A1ELANEHPGDL3MBTL1ATM
Ether SCHEMBL9731245 0.83 AKR1C3 (0.50) ALDH1A1ELANEHPGDL3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6231783-B1 SOLVENT SYSTEMS HAVING IMPROVED PHYSICAL PROPERTIES TO MINIMIZE ENTRY INTO THE ENVIRONMENT AND TO FACILITATE SEPARATIONS AND CLEANING OPERATIONS TO MINIMIZE POLLUTION MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2001-05-15 US disclosed
WO-1997018179-A1 REPLACEMENT SOLVENTS FOR USE IN CHEMICAL SYNTHESIS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1997-05-22 WO disclosed