Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 8/20 | 0.35 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747312 | 0.80 | ALDH1A1 (0.45) | ALDH1A1AKT1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6749515 | 0.80 | AKT1 (0.47) | ALDH1A1AKT1 | |
| SCHEMBL6752021 | 0.77 | ALDH1A1 (0.39) | ALDH1A1AKT1RAB9ANPC1CYP1A2 | |
| SCHEMBL6749081 | 0.77 | ALDH1A1 (0.50) | ALDH1A1AKT1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6747353 | 0.76 | ALDH1A1 (0.43) | ALDH1A1AKT1RAB9ANPC1CYP1A2 | |
| SCHEMBL6752003 | 0.74 | ALDH1A1 (0.41) | ALDH1A1AKT1RAB9ANPC1CYP1A2 | |
| SCHEMBL6749236 | 0.73 | ALDH1A1 (0.41) | ALDH1A1AKT1RAB9APOLBNPC1 | |
| SCHEMBL6747868 | 0.73 | ALDH1A1 (0.43) | ALDH1A1RAB9ANPC1CYP1A2ALPL | |
| SCHEMBL6749181 | 0.72 | BRPF1 (0.41) | ALDH1A1AKT1CYP1A2SMN1; SMN2IDH1 | |
| SCHEMBL6745573 | 0.71 | GAA (0.47) | ALDH1A1AKT1RAB9ANPC1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | ALDH1A1 145/4885HTT 2395/4885ICAM1 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.