Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7143507 | 0.85 | CYP2D6 (0.58) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL1519223 | 0.79 | MEN1 (0.69) | TSHRMEN1KMT2AS1PR1S1PR5 | |
| SCHEMBL15236204 | 0.78 | ALDH1A1 (0.77) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL6623974 | 0.78 | CYP2D6 (0.68) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL16431003 | 0.78 | CYP2D6 (0.78) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2551741 | 0.78 | MEN1 (0.68) | TSHRMEN1KMT2AS1PR1S1PR5 | |
| SCHEMBL2381838 | 0.77 | CYP2D6 (0.67) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL2848889 | 0.76 | SMN1; SMN2 (0.69) | CYP2D6CYP3A4ALDH1A1USP2MAPK1 | |
| SCHEMBL6750537 | 0.76 | OPRM1 (0.56) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL4927933 | 0.76 | CYP2D6 (0.69) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | EISAI CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092737-A1 | Benzopiperidine derivatives | HLA-DRB1, HRH1, HRH2 | CYP2D6 32/4885CHRM2 1292/4885CHRM3 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.