Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 7/20 | 0.62 |
| ▸ | INPP5A | Q14642 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | INPP5B | P32019 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30662803 | 0.89 | INPPL1 (0.52) | INPPL1INPP5AMAPTCYP3A4TUBB4A | |
| SCHEMBL11104314 | 0.80 | ACHE (0.45) | INPPL1INPP5AMAPTCYP3A4TUBB4A | |
| SCHEMBL14175313 | 0.79 | TUBB1 (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27799416 | 0.79 | INPPL1 (0.76) | INPPL1INPP5ACYP3A4INPP5BSRC | |
| SCHEMBL14175306 | 0.78 | CYP1A1 (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28122387 | 0.77 | INPPL1 (0.67) | INPPL1INPP5ACYP3A4INPP5BSRC | |
| SCHEMBL6517656 | 0.75 | MAPT (0.52) | MAPTCYP3A4TUBB4ATUBBTUBA3C | |
| SCHEMBL4186085 | 0.75 | INPPL1 (1.00) | INPPL1INPP5ACYP3A4INPP5BSRC | |
| SCHEMBL9701188 | 0.74 | INPPL1 (0.68) | INPPL1INPP5AMAPTCYP3A4INPP5B | |
| SCHEMBL11336579 | 0.74 | PTGS2 (0.44) | MAPTCYP3A4TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6702705-B1 | Prodrugs activated by targeted catalytic proteins | IGEN INTERNATIONAL, INC. | 2004-03-09 | — | — | US | disclosed |