Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GLS | O94925 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348053 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EGLALMNAAPAF1 | |
| SCHEMBL18157935 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4EGLALMNAAPAF1 | |
| SCHEMBL2608929 | 0.74 | LMNA (0.62) | ALDH1A1KDM4EGLALMNAAPAF1 | |
| SCHEMBL10277762 | 0.73 | — | — | |
| SCHEMBL17489160 | 0.72 | GLS (0.75) | ALDH1A1KDM4EGLALMNAAPAF1 | |
| SCHEMBL16447617 | 0.72 | ALDH1A1 (0.64) | ALDH1A1KDM4EGLALMNAAPAF1 | |
| Hydrochloric Acid SCHEMBL464810 | 0.71 | ALDH1A1 (0.57) | ALDH1A1KDM4EGLALMNAAPAF1 | |
| SCHEMBL14578729 | 0.71 | LMNA (0.64) | ALDH1A1KDM4EGLALMNAAPAF1 | |
| SCHEMBL13045167 | 0.71 | GLS (0.60) | ALDH1A1KDM4EGLALMNAAPAF1 | |
| SCHEMBL13633143 | 0.71 | LMNA (0.59) | ALDH1A1KDM4EGLALMNAAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082464-A1 | Complex polymerization catalysts for the homopolymerization of ethylene and for the copolymerization of ethylene | POLIMERI EUROPA S.P.A. (IT) | 2004-04-29 | — | — | US | disclosed |
| EP-1268500-A1 | COMPLEX POLYMERIZATION CATALYSTS FOR THE HOMOPOLYMERIZATION OF ETHYLENE AND FOR THE COPOLYMERIZATION OF ETHYLENE | Polimeri Europa S.p.A. (IT) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074831-A1 | COMPLEX POLYMERIZATION CATALYSTS FOR THE HOMOPOLYMERIZATION OF ETHYLENE AND FOR THE COPOLYMERIZATION OF ETHYLENE | POLIMERI EUROPA S.P.A. (IT) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082464-A1 | Complex polymerization catalysts for the homopolymerization of ethylene and for the copolymerization of ethylene | ETV6, MVD, ELL | ALDH1A1 2491/4885KDM4E 1274/4885GLA 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.