Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038572 | 0.92 | GPR119 (0.41) | GPR119SLC2A1MCHR1HRH3NOTCH1 | |
| SCHEMBL6812071 | 0.91 | GPR119 (0.42) | GPR119SLC2A1MCHR1HRH3NOTCH1 | |
| SCHEMBL6318034 | 0.85 | KDM4E (0.46) | GPR119NOTCH1MGLLKDM4EPKM | |
| SCHEMBL7038825 | 0.85 | NOTCH1 (0.44) | GPR119SLC2A1NOTCH1MGLLKDM4E | |
| SCHEMBL6750024 | 0.79 | NOTCH1 (0.44) | GPR119NOTCH1MGLLKDM4EPKM | |
| SCHEMBL6831982 | 0.79 | NOTCH1 (0.41) | GPR119NOTCH1MGLLKDM4EPKM | |
| SCHEMBL6831983 | 0.79 | NOTCH1 (0.41) | GPR119NOTCH1MGLLKDM4EPKM | |
| SCHEMBL6817721 | 0.78 | MCHR1 (0.43) | SLC2A1MCHR1HRH3 | |
| SCHEMBL6831986 | 0.78 | KDM4E (0.48) | GPR119NOTCH1MGLLKDM4EPKM | |
| SCHEMBL27459780 | 0.77 | MGLL (0.44) | GPR119NOTCH1MGLLKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043310-B1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LTD (JP) | 2004-06-09 | — | — | EP | disclosed |
| US-6706745-B1 | THERAPY FOR ANTICOAGULATION PLAYS AN IMPORTANT PART IN THE MEDICAL TREATMENT AND PROPHYLAXIS OF THROMBOEMBOLISMS | TEIJIN LIMITED (JP) | 2004-03-16 | — | — | US | disclosed |
| EP-1043310-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |