Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.44 |
| ▸ | CETP | P11597 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | YAP1 | P46937 | 3/20 | 0.43 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318034 | 0.93 | KDM4E (0.46) | KDM4EPKMMGLLTGFBR1CETP | |
| SCHEMBL27459780 | 0.87 | MGLL (0.44) | KDM4EPKMMGLLTGFBR1CETP | |
| SCHEMBL7039054 | 0.82 | MGLL (0.55) | MGLL | |
| SCHEMBL6832947 | 0.81 | CHRM3 (0.44) | USP30PRMT5 | |
| SCHEMBL7038825 | 0.81 | NOTCH1 (0.44) | KDM4EPKMMGLLTGFBR1CETP | |
| SCHEMBL6750024 | 0.81 | NOTCH1 (0.44) | KDM4EPKMMGLLTGFBR1CETP | |
| SCHEMBL6834696 | 0.80 | GPR119 (0.42) | KDM4EPKMMGLLTGFBR1CETP | |
| SCHEMBL6834695 | 0.80 | GPR119 (0.42) | KDM4EPKMMGLLTGFBR1CETP | |
| SCHEMBL7041177 | 0.79 | HRH2 (0.44) | MGLL | |
| SCHEMBL6812071 | 0.79 | GPR119 (0.42) | KDM4EPKMMGLLCETPGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1610665-A | Process for preparing cyanophenylbenzoic acid derivatives | TEIJIN LTD (JP) | 2005-04-27 | — | — | CN | claimed |
| US-20040072866-A1 | Process for preparation of cyanophenylbenzoic acid derivatives | TEIJIN LIMITED (JP) | 2004-04-15 | — | — | US | claimed |
| EP-1361213-A1 | PROCESS FOR PREPARATION OF CYANOPHENYLBENZOIC ACID DERIVATIVES | TEIJIN LIMITED (JP) | 2003-11-12 | — | — | EP | claimed |
| CN-1610665-A | Process for preparing cyanophenylbenzoic acid derivatives | TEIJIN LTD (JP) | 2005-04-27 | — | — | CN | disclosed |
| US-20040072866-A1 | Process for preparation of cyanophenylbenzoic acid derivatives | TEIJIN LIMITED (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1361213-A1 | PROCESS FOR PREPARATION OF CYANOPHENYLBENZOIC ACID DERIVATIVES | TEIJIN LIMITED (JP) | 2003-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072866-A1 | Process for preparation of cyanophenylbenzoic acid derivatives | CCNY, ACLY, IWS1 | KDM4E 522/4885PKM 567/4885MGLL 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.