SCHEMBL675025

SCHEMBL675025

CCC(C)c1cccc(O)c1C=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
HDAC4 P56524 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
GABRA1 P14867 2/20 0.42
GABRB2 P47870 2/20 0.42
RORC P51449 1/20 0.40
ERN1 O75460 2/20 0.36
POLB P06746 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
HPGD P15428 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
FAAH O00519 1/20 0.35
LMNA P02545 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
PTGS1 P23219 1/20 0.35
SLC6A2 P23975 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL954358 0.87 TSHR (0.50) TSHRHDAC4HDAC2HDAC8GABRA1
SCHEMBL8674812 0.85 TSHR (0.42) TSHRHDAC4HDAC2HDAC8GABRA1
SCHEMBL1527132 0.82 GABRA1 (0.54) TSHRHDAC4HDAC2HDAC8GABRA1
SCHEMBL955537 0.81 TSHR (0.44) TSHRHDAC4HDAC2HDAC8GABRA1
SCHEMBL14354427 0.80 GABRA1 (0.42) TSHRHDAC4HDAC2HDAC8GABRA1
SCHEMBL15485172 0.77 TSHR (1.00) TSHRHDAC4HDAC2HDAC8GABRA1
SCHEMBL20721726 0.77 TSHR (1.00) TSHRHDAC4HDAC2HDAC8GABRA1
SCHEMBL282162 0.77 TSHR (1.00) TSHRHDAC4HDAC2HDAC8GABRA1
SCHEMBL6900092 0.76 TSHR (0.52) TSHRHDAC4HDAC2HDAC8GABRA1
SCHEMBL29216343 0.76 PTGS2 (0.43) TSHRGABRA1GABRB2ERN1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476830-B Hardener composition and associated forming process, uncured and cured epoxy resin composition, and article 沙特基础工业全球技术有限公司 2021-07-09 CN claimed
CN-108290386-B Method of forming a cured epoxy material, cured epoxy material formed thereby, and composite core incorporating the cured epoxy material 沙特基础工业全球技术有限公司 2021-05-14 CN claimed
US-20190241698-A1 HARDENER COMPOSITION AND ASSOCIATED FORMING METHOD, UNCURED AND CURED EPOXY RESIN COMPOSITIONS, AND ARTICLE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-08-08 US claimed
EP-3487906-A1 HARDENER COMPOSITION AND ASSOCIATED FORMING METHOD, UNCURED AND CURED EPOXY RESIN COMPOSITIONS, AND ARTICLE SABIC Global Technologies B.V. (NL) 2019-05-29 EP claimed
US-20180319930-A1 METHOD OF FORMING A CURED EPOXY MATERIAL, CURED EPOXY MATERIAL FORMED THEREBY, PHENYLENE ETHER OLIGOMER-ANHYDRIDE REACTION PRODUCT USEFUL IN THE METHOD, AND COMPOSITE CORE INCORPORATING THE CURED EPOXY MATERIAL SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-11-08 US claimed
EP-3377315-A1 METHOD OF FORMING A CURED EPOXY MATERIAL, CURED EPOXY MATERIAL FORMED THEREBY, PHENYLENE ETHER OLIGOMER-ANHYDRIDE REACTION PRODUCT USEFUL IN THE METHOD, AND COMPOSITE CORE INCORPORATING THE CURED EPOXY MATERIAL SABIC Global Technologies B.V. (NL) 2018-09-26 EP claimed
WO-2018022262-A1 HARDENER COMPOSITION AND ASSOCIATED FORMING METHOD, UNCURED AND CURED EPOXY RESIN COMPOSITIONS, AND ARTICLE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-02-01 WO claimed
CN-1589136-A Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups CUTANIX CORP (US) 2005-03-02 CN claimed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 US claimed
EP-3640275-B1 CURABLE EPOXY COMPOSITIONS AND CURED PRODUCTS THEREOF SHPP GLOBAL TECH BV (NL) 2022-06-29 EP disclosed
US-20220145065-A1 CROSS-LINKABLE NETWORK FROM FUNCTIONALIZED POLYETHERIMIDE AND THERMOSET POLYMER RESULTING THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-05-12 US disclosed
EP-3931238-A1 CROSS-LINKABLE NETWORK FROM FUNCTIONALIZED POLYETHERIMIDE AND THERMOSET POLYMER RESULTING THEREFROM SHPP Global Technologies B.V. (NL) 2022-01-05 EP disclosed
CN-109476830-B Hardener composition and associated forming process, uncured and cured epoxy resin composition, and article 沙特基础工业全球技术有限公司 2021-07-09 CN disclosed
CN-108290386-B Method of forming a cured epoxy material, cured epoxy material formed thereby, and composite core incorporating the cured epoxy material 沙特基础工业全球技术有限公司 2021-05-14 CN disclosed
WO-2007044294-A1 POLYMER COMPOSITION, METHOD, AND ARTICLE GENERAL ELECTRIC COMPANY (US) 2007-04-19 WO disclosed
US-20070082987-A1 Poly(arylene ether) composition, method, and article SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2007-04-12 US disclosed
US-20070082986-A1 Polymer composition, method, and article SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) 2007-04-12 US disclosed
US-20070080330-A1 Flame retardant composition and method CITIBANK, N.A., AS COLLATERAL AGENT 2007-04-12 US disclosed
CN-1589136-A Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups CUTANIX CORP (US) 2005-03-02 CN disclosed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments TYR, HRH1, HRH2 TSHR 4382/4885HDAC4 1082/4885HDAC2 697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.