Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 5/20 | 1.00 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.79 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303163 | 0.93 | HDAC3 (0.86) | HDAC6HDAC8HDAC3HDAC11TRPV1 | |
| SCHEMBL5696343 | 0.89 | HDAC1 (1.00) | HDAC6HDAC8HDAC3HDAC11HDAC1 | |
| SCHEMBL1982935 | 0.88 | HDAC6 (0.78) | HDAC6HDAC8HDAC3HDAC11TRPV1 | |
| SCHEMBL7296335 | 0.88 | HDAC6 (0.78) | HDAC6HDAC8HDAC3HDAC11TRPV1 | |
| SCHEMBL23352874 | 0.86 | HDAC3 (0.75) | HDAC6HDAC8HDAC3HDAC11TRPV1 | |
| SCHEMBL4131602 | 0.86 | HDAC3 (0.75) | HDAC6HDAC8HDAC3HDAC11TRPV1 | |
| SCHEMBL7293270 | 0.86 | HDAC3 (0.75) | HDAC6HDAC8HDAC3HDAC11TRPV1 | |
| SCHEMBL7301362 | 0.86 | HDAC3 (0.75) | HDAC6HDAC8HDAC3HDAC11TRPV1 | |
| SCHEMBL1687867 | 0.86 | NPC1 (0.79) | HDAC6HDAC8HDAC3HDAC11TRPV1 | |
| SCHEMBL7294845 | 0.86 | HDAC3 (0.75) | HDAC6HDAC8HDAC3HDAC11TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059442-A1 | MODULATING PLANT RESPONSES TO STRESS AND GROWTH WITH CHEMICALS | REMOTE EPIGENETICS INC. (US) | 2025-03-20 | — | — | WO | claimed |
| EP-4410284-A1 | COMPOUND AND METHOD FOR THE TREATMENT OF ZELLWEGER SPECTRUM DISORDER | Apteeus (FR) | 2024-08-07 | — | — | EP | claimed |
| US-20230391868-A1 | COMPOSITIONS FOR AND METHODS OF TREATING CANCER | THE GEORGE WASHINGTON UNIVERSITY | 2023-12-07 | — | — | US | claimed |
| CN-116510024-A | Composition, preparation method and application thereof | 上海复东生物医药有限责任公司 | 2023-08-01 | — | — | CN | claimed |
| WO-2023096899-A1 | HYDROGEL PHARMACEUTICAL COMPOSITIONS | AMACATHERA (CA) | 2023-06-01 | — | — | WO | claimed |
| US-9115090-B2 | Zn2+-chelating motif-tethered short-chain fatty acids as a novel class of histone deacetylase inhibitors | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2015-08-25 | — | — | US | claimed |
| EP-1660437-B1 | HYDROXAMIC ACID DERIVATIVES AND THE METHOD FOR PREPARING THEREOF | AMOREPACIFIC CORP (KR) | 2008-10-15 | — | — | EP | claimed |
| US-7282522-B2 | Hydroxamic acid derivatives and the method for preparing thereof | AMOREPACIFIC CORPORATION (KR) | 2007-10-16 | — | — | US | claimed |
| US-20070225373-A1 | Zn2Motif-Tethered Short-Chain Fatty Acids as a Novel Class of Histone Deacetylase | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-09-27 | — | — | US | claimed |
| EP-1696898-A2 | ZN 24 -CHELATING MOTIF-TETHERED SHORT-CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-09-06 | — | — | EP | claimed |
| WO-2005055928-A2 | ZN2+ -CHELATING MOTIF-TETHERED SHORT -CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-06-23 | — | — | WO | claimed |
| WO-2025059442-A1 | MODULATING PLANT RESPONSES TO STRESS AND GROWTH WITH CHEMICALS | REMOTE EPIGENETICS INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| CN-115192714-B | Use of HDAC6 inhibitors in the manufacture of a medicament for the treatment of DNMT3A gene-deficient cancers | 沈阳药科大学 | 2024-09-17 | — | — | CN | disclosed |
| WO-2024160990-A1 | COMPOUNDS AND METHOD FOR THE TREATMENT OF ZELLWEGER SPECTRUM DISORDER | APTEEUS (FR) | 2024-08-08 | — | — | WO | disclosed |
| EP-4410284-A1 | COMPOUND AND METHOD FOR THE TREATMENT OF ZELLWEGER SPECTRUM DISORDER | Apteeus (FR) | 2024-08-07 | — | — | EP | disclosed |
| WO-2011103563-A1 | METHODS AND COMPOSITIONS FOR INHIBITING AND PREVENTING THE GROWTH OF MALIGNANT MAST CELLS | ARNO THERAPEUTICS, INC (US) | 2011-08-25 | — | — | WO | disclosed |
| US-20090137679-A1 | ZN2+Chelating Motif-Tethered Short-Chain Fatty Acids as a Novel Class of Histone Deacetylase Inhibitors | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-05-28 | — | — | US | disclosed |
| US-20070225373-A1 | Zn2Motif-Tethered Short-Chain Fatty Acids as a Novel Class of Histone Deacetylase | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-09-27 | — | — | US | disclosed |
| EP-1696898-A2 | ZN 24 -CHELATING MOTIF-TETHERED SHORT-CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005055928-A2 | ZN2+ -CHELATING MOTIF-TETHERED SHORT -CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391868-A1 | COMPOSITIONS FOR AND METHODS OF TREATING CANCER | CD47, HDAC6, HDAC3 | HDAC6 2/4885HDAC8 12/4885HDAC3 3/4885 |
| US-20070225373-A1 | Zn2Motif-Tethered Short-Chain Fatty Acids as a Novel Class of Histone Deacetylase | HDAC1, BAZ2B, HDAC11 | HDAC6 13/4885HDAC8 14/4885HDAC3 6/4885 |
| US-20090137679-A1 | ZN2+Chelating Motif-Tethered Short-Chain Fatty Acids as a Novel Class of Histone Deacetylase Inhibitors | HDAC1, HDAC9, HDAC3 | HDAC6 13/4885HDAC8 9/4885HDAC3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.