Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.78 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.78 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.78 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.78 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982935 | 1.00 | HDAC6 (0.78) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL7303163 | 0.91 | HDAC3 (0.86) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL675041 | 0.88 | HDAC6 (1.00) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL21798720 | 0.87 | KMT2A (0.76) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3679372 | 0.87 | KMT2A (0.76) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5223825 | 0.86 | NR1H4 (0.71) | HDAC6HDAC3HDAC8HDAC11NR1H4 | |
| SCHEMBL21588672 | 0.85 | SMN1; SMN2 (0.76) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL23352874 | 0.84 | HDAC3 (0.75) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL7301362 | 0.84 | HDAC3 (0.75) | HDAC6HDAC3HDAC8HDAC11TRPV1 | |
| SCHEMBL7293270 | 0.84 | HDAC3 (0.75) | HDAC6HDAC3HDAC8HDAC11TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |