Mandipropamid

Mandipropamid

SCHEMBL675075

C#CCOc1ccc(CCNC(=O)[C@@H](OCC#C)c2ccc(Cl)cc2)cc1OC

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.52
ALDH1A1 P00352 3/20 0.51
CNR1 P21554 1/20 0.50
LMNA P02545 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
CTSD P07339 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TP53 P04637 1/20 0.44
THRB P10828 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mandipropamid SCHEMBL29379242 1.00 GAA (0.52) GAAALDH1A1CNR1LMNASMN1; SMN2
Mandipropamid SCHEMBL22338 1.00 GAA (0.52) GAAALDH1A1CNR1LMNASMN1; SMN2
SCHEMBL6227631 0.95 GAA (0.48) GAAALDH1A1CNR1LMNASMN1; SMN2
SCHEMBL6227628 0.95 GAA (0.48) GAAALDH1A1CNR1LMNASMN1; SMN2
SCHEMBL6228713 0.94 GAA (0.50) GAAALDH1A1CNR1LMNASMN1; SMN2
SCHEMBL6228709 0.94 GAA (0.50) GAAALDH1A1CNR1LMNASMN1; SMN2
SCHEMBL13968230 0.94 GAA (0.48) GAAALDH1A1CNR1LMNASMN1; SMN2
SCHEMBL13369734 0.94 GAA (0.48) GAAALDH1A1CNR1LMNASMN1; SMN2
SCHEMBL6230935 0.93 GAA (0.53) GAAALDH1A1CNR1LMNASMN1; SMN2
SCHEMBL1551918 0.93 GAA (0.53) GAAALDH1A1CNR1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4711975-B2 2011-06-29 JP claimed
US-7776892-B2 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the spores germination or mycelium growth by acting on different metabolic routes BAYER CROPSCIENCE S.A. (FR) 2010-08-17 US claimed
WO-2009095242-A2 FUNGICIDAL MIXTURES AND COMPOSITIONS FOR THE CONTROL OF PHYTOPATHOGENIC FUNGI ISAGRO RICERCA S.R.L. (IT) 2009-08-06 WO claimed
EP-1713334-B1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE SPORES GERMINATION OR MYCELIUM GROWTH BY ACTING ON DIFFERENT METABOLIC ROUTES BAYER CROPSCIENCE SA (FR) 2008-07-23 EP claimed
US-20070142444-A1 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the spores germination or mycelium growth by acting on different metabolic routes BAYER CROPSCIENCE S.A. (FR) 2007-06-21 US claimed
EP-1713334-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE SPORES GERMINATION OR MYCELIUM GROWTH BY ACTING ON DIFFERENT METABOLIC ROUTES Bayer CropScience S.A. (FR) 2006-10-25 EP claimed
WO-2005077181-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE SPORES GERMINATION OR MYCELIUM GROWTH BY ACTING ON DIFFERENT METABOLIC ROUTES BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
EP-1444197-B1 NOVEL PHENYL-PROPARGYLETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2005-03-30 EP claimed
US-20050026785-A1 Novel phenyl-propargylether derivatives SYNGENTA CROP PROTECTION, INC. 2005-02-03 US claimed
EP-1444197-A1 NOVEL PHENYL-PROPARGYLETHER DERIVATIVES Syngenta Participations AG (CH) 2004-08-11 EP claimed
WO-2003041728-A9 NOVEL PHENYL-PROPARGYLETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2004-04-22 WO claimed
WO-2003041728-A1 NOVEL PHENYL-PROPARGYLETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2003-05-22 WO claimed
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2022-06-02 US disclosed
EP-3927341-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2021-12-29 EP disclosed
WO-2020201440-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST VIRBAC (FR) 2020-10-08 WO disclosed
EP-3646731-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-05-06 EP disclosed
US-20050026785-A1 Novel phenyl-propargylether derivatives SYNGENTA CROP PROTECTION, INC. 2005-02-03 US disclosed
EP-1444197-A1 NOVEL PHENYL-PROPARGYLETHER DERIVATIVES Syngenta Participations AG (CH) 2004-08-11 EP disclosed
WO-2003041728-A9 NOVEL PHENYL-PROPARGYLETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2004-04-22 WO disclosed
WO-2003041728-A1 NOVEL PHENYL-PROPARGYLETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2003-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168278-A1 LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST P2RX7, CAT, PDE8A GAA 300/4885ALDH1A1 3318/4885CNR1 1067/4885
US-20050026785-A1 Novel phenyl-propargylether derivatives OR10J3, PRXL2A, OSR1 GAA 3350/4885ALDH1A1 1556/4885CNR1 603/4885
US-20070142444-A1 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the spores germination or mycelium growth by acting on different metabolic routes PLPBP, MAOB, CYP51A1 GAA 327/4885ALDH1A1 898/4885CNR1 3528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.