SCHEMBL675478

SCHEMBL675478

CCc1c(C(=O)c2cc(C)cc(C)c2)n(CC2CC=CC2)c(=O)[nH]c1=O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
GRIN1 Q05586 2/20 0.35
GRIN2B Q13224 2/20 0.35
SMN1; SMN2 Q16637 3/20 0.33
ALDH1A1 P00352 2/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6087020 0.91 GRIN1 (0.43) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL7070169 0.89 KMT2A (0.36) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL7067487 0.89 GRIN1 (0.39) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL6087285 0.89 GRIN1 (0.39) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL6088074 0.88 GRIN1 (0.39) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL675171 0.85 KMT2A (0.35) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL13996749 0.85 GAA (0.36) KMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL6086536 0.85 KMT2A (0.36) KMT2AMEN1TDP1GRIN1GRIN2B
SCHEMBL3186190 0.85 TSHR (0.36) KMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL7076081 0.83 GRIN1 (0.34) KMT2AMEN1TDP1GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255968-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY KISER PATRICK F (US) 2025-08-14 US claimed
EP-2734262-B1 INTRAVAGINAL RINGS FOR DRUG DELIVERY KISER PATRICK F (US) 2018-02-28 EP claimed
US-20140209100-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY Kiser, Patrick F. 2014-07-31 US claimed
EP-2734262-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY Kiser, Patrick F. (US) 2014-05-28 EP claimed
US-20130220337-A1 DEVICES AND METHODS FOR INTRAVAGINAL DELIVERY OF DRUGS AND OTHER SUBSTANCES KISER PATRICK F (US) 2013-08-29 US claimed
EP-2605779-A2 DEVICES AND METHODS FOR INTRAVAGINAL DELIVERY OF DRUGS AND OTHER SUBSTANCES The University of Utah Research Foundation (US) 2013-06-26 EP claimed
WO-2013013172-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2013-01-24 WO claimed
WO-2012024605-A2 DEVICES AND METHODS FOR INTRAVAGINAL DELIVERY OF DRUGS AND OTHER SUBSTANCES THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2012-02-23 WO claimed
US-20110045076-A1 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION 2011-02-24 US claimed
EP-2244782-A2 LINEAR ORDER RELEASE POLYMER The University of Utah Research Foundation (US) 2010-11-03 EP claimed
WO-2009094573-A9 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2010-09-16 WO claimed
WO-2009094573-A2 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2009-07-30 WO claimed
US-20250255968-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY KISER PATRICK F (US) 2025-08-14 US disclosed
US-20220409589-A1 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY GENZYME CORP (US) 2022-12-29 US disclosed
EP-2734262-B1 INTRAVAGINAL RINGS FOR DRUG DELIVERY KISER PATRICK F (US) 2018-02-28 EP disclosed
US-20140209100-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY Kiser, Patrick F. 2014-07-31 US disclosed
US-6274732-B1 ALKYLATION SAMJIN PHARMACEUTICAL CO., LTD. (KR) 2001-08-14 US disclosed
JP-2000264878-A PRODUCTION OF 1-[(CYCLOPENT-3-EN-1-YL)METHYL]-5-ETHYL-6-(3,5- DIMETHYLBENZOYL)-2,4-PYRIMIDINEDIONE SAMJIN PHARMACEUTICAL CO LTD 2000-09-26 JP disclosed
EP-1035116-A1 Process for the preparation of 1-[(cyclopent-3-en-1-yl)-methyl]-5-ethyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione Samjin Pharmaceutical Co., Ltd. (KR) 2000-09-13 EP disclosed
US-5922727-A 1-((SUBSTITUTED)CYCLOALK(EN)YLALKYL)-6-((SUB)PHENYL(CARBONYL, SULFIDE, OR OXO))-2,4-PYRIMIDINEDIONE DERIVATIVES HAVING SUPERIOR ANTIVIRAL ACTIVITIES; HIV SAMJIN PHARMACEUTICAL CO., LTD (KR) 1999-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220409589-A1 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY CCR5, CXCR4, CXCR3 KMT2A 3464/4885MEN1 3210/4885TDP1 4428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.