Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804579 | 0.79 | MAOA (0.62) | MAOA | |
| SCHEMBL9201087 | 0.79 | MAOA (0.62) | MAOA | |
| Hydrochloric Acid SCHEMBL5967428 | 0.77 | MAOA (0.61) | MAOA | |
| SCHEMBL671879 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2GAAPKMEPHX1 | |
| SCHEMBL26676923 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAAPKMEPHX1 | |
| SCHEMBL17666275 | 0.75 | MAOA (0.65) | MAOA | |
| SCHEMBL673608 | 0.74 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2GAAPKMMAPT | |
| SCHEMBL6277688 | 0.74 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2GAAPKMIDO1 | |
| Hydrochloric Acid SCHEMBL8841049 | 0.74 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2GAAPKMIDO1 | |
| SCHEMBL11197684 | 0.74 | MEN1 (0.61) | ALDH1A1SMN1; SMN2GAAPKMEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2605801-A1 | IMAGING TUBERCULOSIS WITH PYRAZINAMIDE CONTRAST AGENTS | GE Healthcare UK Limited (GB) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012022812-A1 | IMAGING TUBERCULOSIS WITH PYRAZINAMIDE CONTRAST AGENTS | GE HEALTHCARE LIMITED (GB) | 2012-02-23 | — | — | WO | disclosed |