Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.34 |
| ▸ | TUBB | P07437 | 4/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6515764 | 0.84 | SLC28A1 (0.38) | SLC28A1SLC28A2SLC29A1SLC28A3POLB | |
| SCHEMBL6751346 | 0.80 | SLC28A1 (0.36) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL5144346 | 0.76 | SLC28A1 (0.45) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL27979205 | 0.75 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL17099404 | 0.75 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL151327 | 0.73 | SLC28A1 (0.43) | ALDH1A1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL27831384 | 0.72 | SLC28A1 (0.40) | ALDH1A1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6517571 | 0.72 | TUBB1 (0.32) | ALDH1A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL851503 | 0.71 | SLC28A1 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3POLB | |
| SCHEMBL29084627 | 0.71 | SLC28A1 (0.42) | ALDH1A1SLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6702705-B1 | Prodrugs activated by targeted catalytic proteins | IGEN INTERNATIONAL, INC. | 2004-03-09 | — | — | US | disclosed |