Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PYGM | P11217 | 1/20 | 0.52 |
| ▸ | TK1 | P04183 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753208 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1POLBKMT2APYGM | |
| SCHEMBL27502178 | 0.88 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1POLBKMT2APYGM | |
| SCHEMBL1130181 | 0.84 | LMNA (0.55) | ALDH1A1POLBTK1LMNATSHR | |
| SCHEMBL1027300 | 0.84 | TK1 (0.60) | SMN1; SMN2PYGMTK1LMNACYP1A2 | |
| SCHEMBL3415528 | 0.84 | TK1 (0.60) | SMN1; SMN2PYGMTK1LMNACYP1A2 | |
| SCHEMBL6760136 | 0.84 | LMNA (0.55) | ALDH1A1POLBTK1LMNATSHR | |
| SCHEMBL7701755 | 0.84 | LMNA (0.55) | ALDH1A1POLBTK1LMNATSHR | |
| SCHEMBL1129572 | 0.84 | LMNA (0.55) | ALDH1A1POLBTK1LMNATSHR | |
| SCHEMBL1129570 | 0.84 | LMNA (0.55) | ALDH1A1POLBTK1LMNATSHR | |
| SCHEMBL6752642 | 0.84 | LMNA (0.60) | SMN1; SMN2TK1LMNATSHRPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956021-B1 | L-BETA-DIOXOLANE URIDINE ANALOGS FOR TREATING AND PREVENTING INFECTIONS BY EBV, VZV AND HV-8 | UNIV YALE (US) | 2004-11-03 | — | — | EP | disclosed |
| US-6022876-A | KAPOSI'S SARCOMA; VARICELLA-ZOSTER VIRUS | YALE UNIVERSITY (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0956021-A1 | L-$g(b)-DIOXOLANE URIDINE ANALOGS AND METHODS FOR TREATING AND PREVENTING VIRUS INFECTIONS | YALE UNIVERSITY (US) | 1999-11-17 | — | — | EP | disclosed |
| US-5792773-A | L-β-dioxolane uridine analog administration for treating Epstein-Barr virus infection | YALE UNIVERSITY (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1998020879-A1 | L-β-DIOXOLANE URIDINE ANALOGS AND METHODS FOR TREATING AND PREVENTING VIRUS INFECTIONS | YALE UNIVERSITY (US) | 1998-05-22 | — | — | WO | disclosed |