Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753602 | 1.00 | KDM1A (0.49) | KDM1AMAOAMAOBMEN1KMT2A | |
| SCHEMBL8332789 | 0.82 | SLC9A1 (0.51) | MEN1KMT2AHTR2CALDH1A1HPGD | |
| SCHEMBL7002740 | 0.80 | MAOA (0.51) | KDM1AMAOAMAOBMAPTHTR2C | |
| SCHEMBL7003744 | 0.78 | DRD2 (0.42) | L3MBTL1SLC6A3ALDH1A1LMNADRD2 | |
| SCHEMBL7096961 | 0.76 | CHRNA7 (0.49) | KDM1AMAOAMAOB | |
| SCHEMBL7096959 | 0.76 | CHRNA7 (0.49) | KDM1AMAOAMAOB | |
| SCHEMBL11064728 | 0.75 | KDM1A (0.72) | KDM1AMAOAMAOBMAPTHTR2C | |
| SCHEMBL11064726 | 0.75 | KDM1A (0.72) | KDM1AMAOAMAOBMAPTHTR2C | |
| SCHEMBL7130677 | 0.75 | KDM1A (0.45) | KDM1AMAOAMAOBMEN1KMT2A | |
| SCHEMBL7446687 | 0.75 | KDM1A (0.45) | KDM1AMAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713483-B1 | TREATING PLATELET AGGREGATION DISORDER | ASTRAZENECA AB (SE) | 2004-03-30 | — | — | US | disclosed |
| EP-1232156-B1 | [1,2,3]-TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2003-06-04 | — | — | EP | disclosed |