SCHEMBL675376

SCHEMBL675376

Cc1cc(C)cc(C(=O)c2c(C(C)C)c(=O)[nH]c(=O)n2CC2=CCCC2)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
TDP1 Q9NUW8 3/20 0.35
MAPT P10636 5/20 0.33
KDM4E B2RXH2 3/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 8/20 0.32
HSD17B10 Q99714 3/20 0.32
USP2 O75604 2/20 0.32
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 4/20 0.32
NPSR1 Q6W5P4 2/20 0.31
ALOX15 P16050 2/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2471874 0.85 MEN1 (0.36) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL6088109 0.82 KMT2A (0.37) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL12752174 0.80 KMT2A (0.40) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL6089258 0.80 KMT2A (0.41) MEN1KMT2AMAPTKDM4EATM
SCHEMBL12752290 0.79 B3GNT2 (0.41) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL12752183 0.79 KMT2A (0.47) MEN1KMT2ATDP1MAPTKDM4E
SCHEMBL2469145 0.78 ALDH1A1 (0.32) MEN1KMT2AMAPTALDH1A1HSD17B10
SCHEMBL2470798 0.78 ALDH1A1 (0.32) MAPTALDH1A1HSD17B10SMN1; SMN2ALOX15
SCHEMBL12752190 0.78 KMT2A (0.39) MEN1KMT2ATDP1MAPTALDH1A1
SCHEMBL6088185 0.78 KMT2A (0.37) MEN1KMT2ATDP1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255968-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY KISER PATRICK F (US) 2025-08-14 US claimed
EP-2734262-B1 INTRAVAGINAL RINGS FOR DRUG DELIVERY KISER PATRICK F (US) 2018-02-28 EP claimed
US-20140209100-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY Kiser, Patrick F. 2014-07-31 US claimed
EP-2734262-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY Kiser, Patrick F. (US) 2014-05-28 EP claimed
US-20130220337-A1 DEVICES AND METHODS FOR INTRAVAGINAL DELIVERY OF DRUGS AND OTHER SUBSTANCES KISER PATRICK F (US) 2013-08-29 US claimed
EP-2605779-A2 DEVICES AND METHODS FOR INTRAVAGINAL DELIVERY OF DRUGS AND OTHER SUBSTANCES The University of Utah Research Foundation (US) 2013-06-26 EP claimed
WO-2013013172-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2013-01-24 WO claimed
WO-2012024605-A2 DEVICES AND METHODS FOR INTRAVAGINAL DELIVERY OF DRUGS AND OTHER SUBSTANCES THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2012-02-23 WO claimed
EP-1986651-B1 USE OF A PYRIMIDINEDIONE DERIVATIVE FOR PREVENTING OR TREATING HEPATITIS C SAMJIN PHARM CO LTD (KR) 2011-10-05 EP claimed
US-20110045076-A1 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION 2011-02-24 US claimed
US-7851479-B2 Use of pyrimidinedione derivative for preventing or treating hepatitis C SAMJIN PHARM. CO., LTD. (KR) 2010-12-14 US claimed
EP-2244782-A2 LINEAR ORDER RELEASE POLYMER The University of Utah Research Foundation (US) 2010-11-03 EP claimed
WO-2009094573-A9 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2010-09-16 WO claimed
WO-2009094573-A2 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2009-07-30 WO claimed
US-20090023764-A1 Use of Pyrimidinedione Derivative for Preventing or Treating Hepatitis C SAMJIN PHARM. CO., LTD. (KR) 2009-01-22 US claimed
US-20250255968-A1 INTRAVAGINAL DEVICES FOR DRUG DELIVERY KISER PATRICK F (US) 2025-08-14 US disclosed
EP-2734262-B1 INTRAVAGINAL RINGS FOR DRUG DELIVERY KISER PATRICK F (US) 2018-02-28 EP disclosed
WO-2009094573-A2 LINEAR ORDER RELEASE POLYMER THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2009-07-30 WO disclosed
US-20090023764-A1 Use of Pyrimidinedione Derivative for Preventing or Treating Hepatitis C SAMJIN PHARM. CO., LTD. (KR) 2009-01-22 US disclosed
US-20090023764-A1 Use of Pyrimidinedione Derivative for Preventing or Treating Hepatitis C SAMJIN PHARM. CO., LTD. (KR) 2009-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023764-A1 Use of Pyrimidinedione Derivative for Preventing or Treating Hepatitis C DPYD, UMPS, TYMP MEN1 4693/4885KMT2A 4444/4885TDP1 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.