Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 3/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759794 | 0.89 | AURKA (0.46) | PPARGCYP2C9TSHRKDM4ELMNA | |
| SCHEMBL6628576 | 0.80 | CYP2C9 (0.56) | PPARGCYP2C9TSHRKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6756942 | 0.78 | GRIN2D (0.44) | PPARGCYP2C9TSHRKDM4ELMNA | |
| SCHEMBL6803374 | 0.78 | PPARG (0.45) | PPARGCYP2C9TSHRKDM4ELMNA | |
| SCHEMBL6757803 | 0.77 | DRD2 (0.49) | PPARGCYP2C9TSHRKDM4ERAB9A | |
| SCHEMBL678882 | 0.77 | ALDH1A1 (0.59) | PPARGCYP2C9TSHRLMNARAB9A | |
| SCHEMBL6804905 | 0.76 | KDM4E (0.54) | PPARGCYP2C9TSHRKDM4ELMNA | |
| SCHEMBL6808746 | 0.76 | ROCK2 (0.48) | PPARGCYP2C9TSHRKDM4ELMNA | |
| SCHEMBL6756748 | 0.76 | KDM4E (0.49) | PPARGCYP2C9TSHRKDM4ELMNA | |
| SCHEMBL6759795 | 0.76 | CYP2C9 (0.50) | PPARGCYP2C9TSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | H1-2, H1-0, H1-3 | PPARG 1878/4885CYP2C9 2122/4885TSHR 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.