Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | SCN1A | P35498 | 2/20 | 0.64 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.64 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | PRKCG | P05129 | 1/20 | 0.56 |
| ▸ | PRKCB | P05771 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.56 |
| ▸ | PRKACG | P22612 | 1/20 | 0.56 |
| ▸ | PRKACB | P22694 | 1/20 | 0.56 |
| ▸ | PRKCH | P24723 | 1/20 | 0.56 |
| ▸ | PRKCI | P41743 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238847 | 0.90 | PRKD3 (0.64) | ALDH1A1SCN1ASCN2ASCN3ACYP1A2 | |
| SCHEMBL11629096 | 0.89 | SCN1A (0.60) | ALDH1A1SCN1ASCN2ASCN3ACYP1A2 | |
| SCHEMBL6754556 | 0.86 | ALDH1A1 (0.69) | ALDH1A1SCN1ASCN2ASCN3ACYP1A2 | |
| SCHEMBL18257232 | 0.83 | HDAC4 (0.76) | ALDH1A1CYP3A4CYP2C19HSD17B10HDAC4 | |
| SCHEMBL11626888 | 0.82 | CYP3A4 (0.68) | ALDH1A1SCN1ASCN2ASCN3ACYP1A2 | |
| Hydrochloric Acid SCHEMBL11626592 | 0.81 | SCN1A (0.69) | ALDH1A1SCN1ASCN2ASCN3ACYP1A2 | |
| SCHEMBL29141930 | 0.81 | CYP3A4 (0.74) | ALDH1A1SCN1ASCN2ASCN3ACYP1A2 | |
| SCHEMBL10676001 | 0.81 | SCN1A (0.51) | ALDH1A1SCN1ASCN2ASCN3ACYP1A2 | |
| SCHEMBL8893081 | 0.81 | NPY5R (0.72) | ALDH1A1SCN1ASCN2ASCN3ACYP1A2 | |
| SCHEMBL27488281 | 0.80 | CYP1A2 (0.72) | ALDH1A1SCN1ASCN2ASCN3ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713473-B1 | 6-CARBAMATE-1,2,3,4-TETRAHYDROCARBAZOLE DERIVATIVES; AFFINITY FOR NEUROPEPTIDE Y RECEPTORS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1184373-A1 | TRICYCLIC COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-03-06 | — | — | EP | disclosed |