Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 8/20 | 0.50 |
| ▸ | GABRD | O14764 | 8/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.50 |
| ▸ | GABRE | P78334 | 8/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.45 |
| ▸ | SRC | P12931 | 3/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650164 | 0.89 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2649935 | 0.88 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2649958 | 0.86 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1761724 | 0.85 | KDR (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8009170 | 0.78 | FGFR1 (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1761539 | 0.78 | GABRA1 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2644190 | 0.78 | GABRA1 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1761861 | 0.78 | GABRA1 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3783100 | 0.77 | DRD2 (0.68) | HPGDDRD2DRD3TBK1PRKDC | |
| SCHEMBL1762149 | 0.75 | HPGD (0.56) | HPGDFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710044-B2 | Technical field | NEUROSEARCH A/S (DK) | 2004-03-23 | — | — | US | claimed |