Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.55 |
| ▸ | CYP2E1 | P05181 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 6/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755644 | 0.89 | LMNA (0.52) | MAPTLMNAHTTCYP1A2CYP2D6 | |
| SCHEMBL6587918 | 0.88 | MAPT (0.66) | MAPTLMNAHTTCYP1A2CYP2D6 | |
| SCHEMBL6586332 | 0.86 | MAPT (0.65) | MAPTLMNAHTTCYP1A2CYP2D6 | |
| SCHEMBL6757973 | 0.84 | HSD17B10 (0.56) | MAPTLMNAHTTCYP1A2CYP2D6 | |
| SCHEMBL14311148 | 0.81 | LMNA (0.57) | MAPTLMNAHTTCYP1A2CYP2D6 | |
| SCHEMBL6759851 | 0.80 | BCHE (0.71) | MAPTLMNAHTTNPC1RAB9A | |
| SCHEMBL6759921 | 0.80 | BCHE (0.71) | MAPTLMNAHTTNPC1RAB9A | |
| SCHEMBL19344591 | 0.79 | CYP1A2 (0.53) | MAPTLMNAHTTCYP1A2CYP2D6 | |
| SCHEMBL29703200 | 0.78 | CYP1A2 (0.66) | MAPTLMNAHTTCYP1A2CYP2D6 | |
| SCHEMBL10492884 | 0.78 | HRH4 (0.70) | MAPTLMNAHTTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |