Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 6/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 6/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14304934 | 0.93 | RAB9A (0.63) | HSD17B10RAB9AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL6757965 | 0.89 | RAB9A (0.45) | HSD17B10RAB9AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL6755646 | 0.84 | MAPT (0.65) | RAB9AHPGDSMN1; SMN2CYP1A2CYP2E1 | |
| SCHEMBL6759921 | 0.80 | BCHE (0.71) | RAB9AHPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL6759851 | 0.80 | BCHE (0.71) | RAB9AHPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL16198322 | 0.80 | BCHE (0.51) | HSD17B10RAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL19344591 | 0.79 | CYP1A2 (0.53) | HSD17B10RAB9ACYP1A2CYP2E1CYP3A4 | |
| SCHEMBL9877888 | 0.78 | HSD17B10 (0.48) | HSD17B10RAB9AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL6604233 | 0.78 | MAPT (0.54) | HSD17B10RAB9AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL10513585 | 0.77 | HPGD (0.47) | HSD17B10RAB9AHPGDSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |