SCHEMBL675699

SCHEMBL675699

Cc1ccccc1C(=O)C(O)=Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
RAB9A P51151 2/20 0.47
TSHR P16473 1/20 0.46
AKR1C3 P42330 1/20 0.46
HPGD P15428 1/20 0.44
GPR52 Q9Y2T5 1/20 0.44
ERCC5 P28715 1/20 0.43
FEN1 P39748 1/20 0.43
MAPT P10636 4/20 0.43
PLA2G1B P04054 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5087955 0.86 NPC1 (0.51) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A
SCHEMBL4865622 0.84 AKR1C3 (0.58) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL11774603 0.81 ALDH1A1 (0.56) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL1073512 0.81 MAPT (0.55) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL11775173 0.81 ALDH1A1 (0.56) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL778665 0.78 KDM4E (0.48) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL38659501 0.78 MCL1 (0.57) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL7200630 0.77 NPC1 (0.53) KDM4EMEN1KMT2AALDH1A1RAB9A
SCHEMBL29425530 0.77 HPGD (0.54) KDM4EALDH1A1SMN1; SMN2TSHRHPGD
SCHEMBL166603 0.77 HPGD (0.54) KDM4EALDH1A1SMN1; SMN2TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108883041-B Personal care compositions comprising hair repair blends ELC 管理有限责任公司 2022-03-01 CN claimed
EP-3407858-B1 A METHOD FOR TREATING THE APPEARANCE OF THINNING HAIR ELC MAN LLC (US) 2021-10-13 EP claimed
EP-3407857-B1 PERSONAL CARE COMPOSITION COMPRISING A HAIR RESTORATIVE BLEND ELC MAN LLC (US) 2020-10-28 EP claimed
US-20200268770-A1 PHARMACEUTICAL COMPOSITION USED FOR TREATING METABOLIC SYNDROME DISORDERS, INFECTIOUS DISEASES, AND COMPLICATIONS THEREOF MONKAM NITCHEU GUY FAUSTIN (FR) 2020-08-27 US claimed
EP-3565536-A1 PHARMACEUTICAL COMPOSITION USED FOR TREATING METABOLIC SYNDROME DISORDERS, INFECTIOUS DISEASES, AND COMPLICATIONS THEREOF Monkam Nitcheu, Guy Faustin (FR) 2019-11-13 EP claimed
US-10292997-B2 Compositions and methods for stimulating wound healing Rastein, Daniel N. (US) 2019-05-21 US claimed
WO-2018127748-A1 PHARMACEUTICAL COMPOSITION USED FOR TREATING METABOLIC SYNDROME DISORDERS, INFECTIOUS DISEASES, AND COMPLICATIONS THEREOF MONKAM NITCHEU GUY FAUSTIN (FR) 2018-07-12 WO claimed
CN-107115414-A Nutriment for preventing and treating diabetes B is combined 刘新丰 2017-09-01 CN claimed
EP-1755401-B1 DIETARY SUPPLEMENTS CONTAINING EXTRACTS OF CINNAMON AND METHODS OF USING SAME TO ENHANCE CREATINE TRANSPORT IN INGREDIENTS INC (US) 2016-11-23 EP claimed
EP-3038474-A1 NUTRACEUTICAL COMBINATION FOR PREVENTION AND TREATMENT OF TYPE 2 DIABETES Liu, Charles H. (US) 2016-07-06 EP claimed
EP-1755401-A1 DIETARY SUPPLEMENTS CONTAINING EXTRACTS OF CINNAMON AND METHODS OF USING SAME TO ENHANCE CREATINE TRANSPORT MILLER, Peter (US) 2007-02-28 EP claimed
WO-2006079056-A1 HERBAL COMPOSITIONS CONTAINING HOODIA HOLT STEPHEN (US) 2006-07-27 WO claimed
US-20060159773-A1 Herbal compositions containing hoodia HOLT STEPHEN 2006-07-20 US claimed
WO-2006020091-A2 DIETARY SUPPLEMENTS CONTAINING EXTRACTS OF CINNAMON AND METHODS OF USING SAME TO PROMOTE WEIGHT LOSS INTEGRITY NUTRACEUTICALS INTERNATIONAL (US) 2006-02-23 WO claimed
US-20060013361-A1 Method for measurement of the three-dimensional density distribution in bones Siemens Healthineers Ag (DE) 2006-01-19 US claimed
US-20060013903-A1 Dietary supplements containing extracts of cinnamon and methods of using same to promote weight loss IN INGREDIENTS, INC. 2006-01-19 US claimed
US-6967030-B2 Formulation for insulin and glucose control WRIGHT JONATHAN V 2005-11-22 US claimed
WO-2005099455-A1 DIETARY SUPPLEMENTS CONTAINING EXTRACTS OF CINNAMON AND METHODS OF USING SAME TO ENHANCE CREATINE TRANSPORT MILLER PETER (US) 2005-10-27 WO claimed
US-20040224035-A1 Dietary supplements containing extracts of cinnamon and methods of using same to enhance creatine transport IN INGREDIENTS, INC. 2004-11-11 US claimed
US-20040137090-A1 Formulation for insulin and glucose control WRIGHT JONATHAN V (US) 2004-07-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060159773-A1 Herbal compositions containing hoodia CBX2, CBX7, CYP46A1 KDM4E 2105/4885MEN1 2051/4885KMT2A 2864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.