Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | PYGL | P06737 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | USP10 | Q14694 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587408 | 0.91 | CTSV (0.58) | ALDH1A1NPSR1POLBMEN1KMT2A | |
| SCHEMBL9096671 | 0.88 | TDP1 (0.59) | ALDH1A1NPSR1MEN1KMT2APYGL | |
| SCHEMBL5214818 | 0.88 | MAPT (0.56) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL9234021 | 0.87 | ALDH1A1 (0.52) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL6757005 | 0.86 | PYGL (0.56) | ALDH1A1NPSR1HPGDPOLBMEN1 | |
| SCHEMBL3509871 | 0.86 | MEN1 (0.68) | ALDH1A1NPSR1HPGDPOLBMEN1 | |
| SCHEMBL31504041 | 0.83 | POLB (0.69) | ALDH1A1NPSR1POLBMEN1KMT2A | |
| SCHEMBL570064 | 0.82 | TDP1 (0.57) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL28490919 | 0.81 | TDP1 (0.48) | ALDH1A1NPSR1MEN1KMT2APYGL | |
| SCHEMBL30317914 | 0.81 | TDP1 (0.48) | ALDH1A1NPSR1MEN1KMT2APYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720424-B1 | VEGF (VASCULAR ENDOTHELIAL GROWTH FACTOR) RECEPTOR ANTAGONISTS AND ANGIOGENESIS INHIBITORS SUPPRESS VASCULAR HYPERPERMEABILITY; PHENYLALKYLCARBONYL SUBSTITUENT ON THE AMINO | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| EP-1193246-A1 | AMINOBENZOIC ACID DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-04-03 | — | — | EP | disclosed |