Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.52 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.49 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801724 | 1.00 | TSHR (0.69) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL2249845 | 0.86 | TSHR (0.67) | TSHRALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL14535420 | 0.83 | ALDH1A1 (0.59) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL14701528 | 0.83 | ALDH1A1 (0.59) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL12322211 | 0.81 | ALDH1A1 (0.58) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL13072325 | 0.81 | ALDH1A1 (0.58) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL186230 | 0.81 | LMNA (0.61) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL186416 | 0.81 | LMNA (0.61) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL186238 | 0.81 | LMNA (0.61) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL13947719 | 0.80 | ALDH1A1 (0.56) | TSHRALDH1A1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713652-B1 | ALKALI METAL OR ALKALINE EARTH METAL HYDROXIDE IN THE PRESENCE OF A POLYOL OR AMINO ALCOHOL | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-30 | — | — | US | disclosed |