Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.52 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.49 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757115 | 1.00 | TSHR (0.69) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL2249845 | 0.86 | TSHR (0.67) | TSHRALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL14535420 | 0.83 | ALDH1A1 (0.59) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL14701528 | 0.83 | ALDH1A1 (0.59) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL12322211 | 0.81 | ALDH1A1 (0.58) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL13072325 | 0.81 | ALDH1A1 (0.58) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL186230 | 0.81 | LMNA (0.61) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL186416 | 0.81 | LMNA (0.61) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL186238 | 0.81 | LMNA (0.61) | TSHRALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL13947719 | 0.80 | ALDH1A1 (0.56) | TSHRALDH1A1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592488-B2 | Method for preparing optically active amines | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2009-09-22 | — | — | US | disclosed |
| US-20090035830-A1 | Method for Preparing Optically Active Amines | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2009-02-05 | — | — | US | disclosed |
| EP-1163206-A1 | METHOD FOR HYDROLYZING OPTICALLY ACTIVE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056699-A1 | METHOD FOR HYDROLYZING OPTICALLY ACTIVE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090035830-A1 | Method for Preparing Optically Active Amines | CEL, NAAA, LIPA | TSHR 2334/4885ALDH1A1 482/4885LMNA 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.