Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13182507 | 0.83 | MLKL (0.52) | ALPLMAPK1ALDH1A1IDO1POLB | |
| SCHEMBL6753926 | 0.81 | ALPL (0.54) | ALPLMAPK1ALDH1A1IDO1POLB | |
| SCHEMBL5852590 | 0.81 | ALDH1A1 (0.56) | ALPLMAPK1ALDH1A1IDO1POLB | |
| SCHEMBL3161814 | 0.81 | ALDH1A1 (0.59) | ALPLMAPK1ALDH1A1IDO1POLB | |
| SCHEMBL30583063 | 0.81 | ALDH1A1 (0.59) | ALPLMAPK1ALDH1A1IDO1POLB | |
| SCHEMBL28890917 | 0.80 | TNKS2 (0.56) | ALDH1A1KMT2A | |
| SCHEMBL16756501 | 0.79 | ALPL (0.58) | ALPLMAPK1ALDH1A1IDO1POLB | |
| SCHEMBL3397595 | 0.79 | ALPL (0.58) | ALPLMAPK1ALDH1A1IDO1POLB | |
| SCHEMBL16756243 | 0.79 | ALPL (0.58) | ALPLMAPK1ALDH1A1IDO1POLB | |
| SCHEMBL1284420 | 0.79 | TAAR1 (0.59) | ALPLMAPK1ALDH1A1IDO1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |