Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699278 | 0.91 | ALDH1A1 (0.35) | — | |
| SCHEMBL6864215 | 0.76 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL1032309 | 0.74 | SLC18A3 (0.34) | AR | |
| SCHEMBL1028679 | 0.74 | SLC18A3 (0.34) | AR | |
| SCHEMBL1032476 | 0.74 | SLC18A3 (0.34) | AR | |
| SCHEMBL5557815 | 0.73 | ALDH1A1 (0.42) | ARJAK3FFAR1F10 | |
| SCHEMBL9507055 | 0.73 | CHKA (0.41) | JAK3 | |
| SCHEMBL550942 | 0.71 | USP2 (0.55) | — | |
| SCHEMBL1901765 | 0.71 | L3MBTL3 (0.32) | — | |
| SCHEMBL1031339 | 0.71 | AR (0.42) | ARJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716984-B2 | CONTACTING PHOSPHINE COMPOUND OFTHE FORMULA XPR1R2, WHEREIN X IS A HALOGEN, WITH THE SOLID SUPPORT, RESULTING IN THE P IN THE PHOSPHINE ATTACHED INDIRECTLY OR DIRECTLY TO SOLID SUPPORT VIA A COVALENT BONDS, AND REPLACING R1 OR R2 GROUPS | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-04-06 | — | — | US | claimed |
| US-20020077479-A1 | Polymer-supported synthesis of heteroatom bidentate ligands for catalysis | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-06-20 | — | — | US | claimed |
| US-9567355-B2 | Hepatitis C inhibitors and uses thereof | ABBVIE INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-20160355530-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | ABBVIE INC. | 2016-12-08 | — | — | US | disclosed |
| US-9453007-B2 | Hepatitis C inhibitors and uses thereof | ABBVIE INC. (US) | 2016-09-27 | — | — | US | disclosed |
| US-20160002213-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | ABBVIE INC. | 2016-01-07 | — | — | US | disclosed |
| US-9173887-B2 | Hepatitis C inhibitors and uses thereof | ABBVIE INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20140038919-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | ABBVIE INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-6716984-B2 | CONTACTING PHOSPHINE COMPOUND OFTHE FORMULA XPR1R2, WHEREIN X IS A HALOGEN, WITH THE SOLID SUPPORT, RESULTING IN THE P IN THE PHOSPHINE ATTACHED INDIRECTLY OR DIRECTLY TO SOLID SUPPORT VIA A COVALENT BONDS, AND REPLACING R1 OR R2 GROUPS | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-04-06 | — | — | US | disclosed |
| US-20020077479-A1 | Polymer-supported synthesis of heteroatom bidentate ligands for catalysis | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002213-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | HAVCR2, HCCS, SLC10A1 | AR 4272/4885JAK3 187/4885FFAR1 4626/4885 |
| US-20140038919-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | HAVCR2, HCCS, SLC10A1 | AR 4272/4885JAK3 187/4885FFAR1 4626/4885 |
| US-20160355530-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | HAVCR2, HCCS, SLC10A1 | AR 4272/4885JAK3 187/4885FFAR1 4626/4885 |
| US-20020077479-A1 | Polymer-supported synthesis of heteroatom bidentate ligands for catalysis | PARG, PCNA, PARN | AR 3013/4885JAK3 3689/4885FFAR1 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.