SCHEMBL6757899

SCHEMBL6757899

[CH2]CC(C=O)Oc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
TSHR P16473 2/20 0.34
PPARG P37231 9/20 0.34
PPARA Q07869 9/20 0.34
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
THRB P10828 1/20 0.33
SLC6A4 P31645 1/20 0.33
ALOX15 P16050 1/20 0.32
KCNA3 P22001 1/20 0.32
LTA4H P09960 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821667 0.81 CYP2C19 (0.41) MTNR1AMTNR1BTSHRPPARGPPARA
SCHEMBL11328284 0.80 MTNR1A (0.39) MTNR1AMTNR1BPPARGPPARALMNA
SCHEMBL2123805 0.80 MTNR1A (0.39) MTNR1AMTNR1BTSHRPPARGPPARA
SCHEMBL11160064 0.78 PPARG (0.47) PPARGPPARA
SCHEMBL19312195 0.77 CA4 (0.37) MTNR1AMTNR1BTSHRPPARGPPARA
SCHEMBL25241634 0.74 CTSK (0.41) TSHRPPARGPPARALTA4H
SCHEMBL997312 0.74 PPARG (0.38) MTNR1AMTNR1BTSHRPPARGPPARA
SCHEMBL9720427 0.72 CTRC (0.43) LMNAKMT2ASLC6A4LTA4HMAOA
SCHEMBL5707972 0.72 CTRC (0.43) LMNAKMT2ASLC6A4LTA4HMAOA
SCHEMBL1322499 0.72 CTRC (0.43) LMNAKMT2ASLC6A4LTA4HMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0690855-A1 BENZOPYRANES AS POTASSIUM CHANNEL OPENERS PFIZER LTD (GB) 1996-01-10 EP claimed
US-20040166450-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. 2004-08-26 US disclosed
US-6770433-B2 LEAST ONE OF THE DYE CHROMOPHORES IS A METHINE DYE CHROMOPHORE CONTAINING A BASIC NUCLEUS COMPRISING A MONOCYCLIC HETEROCYCLIC RING. FUJI PHOTO FILM CO., LTD. (JP) 2004-08-03 US disclosed
US-20030068591-A1 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2003-04-10 US disclosed