SCHEMBL114687

SCHEMBL114687

C=CC(=O)NCCC[Si](C)(OCC)OCC

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 2/20 0.54
ZDHHC2 Q9UIJ5 1/20 0.54
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TGM2 P21980 8/20 0.38
GAA P10253 1/20 0.38
KMT5A Q9NQR1 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 2/20 0.31
ATM Q13315 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31351451 0.87 ZDHHC20 (0.54) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL1659840 0.85 ZDHHC20 (0.56) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL13789527 0.85 ZDHHC20 (0.36) ZDHHC20ZDHHC2ALDH1A1CA12CA1
SCHEMBL675801 0.83 ZDHHC20 (0.53) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL19712267 0.82 APEX1 (0.38) ZDHHC20ZDHHC2ALDH1A1MAPTKMT2A
SCHEMBL1285506 0.81 ZDHHC20 (0.51) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL6067393 0.81 TSHR (0.43) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL24843397 0.81 ALDH1A1 (0.53) ZDHHC20ZDHHC2ALDH1A1
SCHEMBL28056045 0.81 ZDHHC20 (0.51) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL26430747 0.81 ZDHHC20 (0.40) ZDHHC20ZDHHC2ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025023143-A1 GLASS CLOTH TREATMENT LIQUID AND SURFACE TREATED GLASS CLOTH 信越化学工業株式会社 2025-01-30 WO disclosed
US-20120065319-A1 Elastomer Compositions Modified By Silanes DOW CORNING EUROPE SA (BE) 2012-03-15 US disclosed
EP-2424739-A1 ELASTOMER COMPOSITIONS MODIFIED BY SILANES Dow Corning Corporation (US) 2012-03-07 EP disclosed
WO-2010125124-A1 ELASTOMER COMPOSITIONS MODIFIED BY SILANES DOW CORNING CORPORATION (US) 2010-11-04 WO disclosed