SCHEMBL675802

SCHEMBL675802

CC=CC(=O)OC[SiH](OCCC)OCCC

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.43
ATM Q13315 1/20 0.41
GSTP1 P09211 1/20 0.33
APP P05067 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALOX5 P09917 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL551679 0.85 HCAR2 (0.39) HCAR2ATMGSTP1MAPTNPSR1
SCHEMBL17536049 0.84 HCAR2 (0.46) HCAR2ATMGSTP1APPMAPT
SCHEMBL64876 0.81 ATM (0.50) HCAR2ATMAPPMAPTRAB9A
SCHEMBL108962 0.80 TSHR (0.53) HCAR2ATMHPGDTSHR
SCHEMBL552010 0.79 GSTP1 (0.37) HCAR2ATMGSTP1
SCHEMBL182848 0.78
SCHEMBL16522478 0.78
SCHEMBL182849 0.78
SCHEMBL2772566 0.78 HCAR2 (0.37) HCAR2ATMTSHR
SCHEMBL2415583 0.75 ALDH1A1 (0.46) HCAR2ATMRAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023113779-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. (US) 2023-06-22 WO disclosed
US-20230183273-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. 2023-06-15 US disclosed
EP-2992909-B1 METAL MEDICAL DEVICE SUMITOMO RUBBER IND (JP) 2019-02-13 EP disclosed
US-10092680-B2 Metal medical device SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2018-10-09 US disclosed
EP-2992909-A1 METAL MEDICAL DEVICE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-03-09 EP disclosed
US-20160058919-A1 METAL MEDICAL DEVICE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-03-03 US disclosed
US-8317220-B2 Curable coating compositions DOW CORNING CORPORATION (US) 2012-11-27 US disclosed
CN-101226329-B Radiation sensitive resin composition, laminated insulating film, micro lens and preparation method thereof JSR CORP 2012-09-05 CN disclosed
US-20120071052-A1 CURABLE COATING COMPOSITIONS DOW TORAY CO., LTD. (JP) 2012-03-22 US disclosed
US-8058190-B2 Curable coating compositions DOW CORNING CORPORATION (US) 2011-11-15 US disclosed
EP-1846480-B1 CURABLE COATING COMPOSITIONS DOW CORNING (US) 2008-10-22 EP disclosed
US-20080003370-A1 Curable Coating Compositions DOW CORNING CORPORATION 2008-01-03 US disclosed
EP-1846480-A1 CURABLE COATING COMPOSITIONS Dow Corning Corporation (US) 2007-10-24 EP disclosed
WO-2006083339-A1 CURABLE COATING COMPOSITIONS DOW CORNING CORPORATION (US) 2006-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183273-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME SSRP1, RPLP2, RPLP1 HCAR2 1011/4885ATM 1387/4885GSTP1 608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.