SCHEMBL675822

SCHEMBL675822

Cc1cc(C(C)(C)c2ccc(O)c(C(C)(C)c3cc(C)c(O)c(C)c3)c2)cc(C)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.62
ALOX15 P16050 4/20 0.51
ALOX12 P18054 2/20 0.51
KLF10 Q13118 1/20 0.46
RORC P51449 1/20 0.42
ESR2 Q92731 6/20 0.41
AR P10275 3/20 0.40
HSD17B10 Q99714 4/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 2/20 0.39
TSHR P16473 2/20 0.39
RECQL P46063 2/20 0.39
CASP1 P29466 1/20 0.39
HIF1A Q16665 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR6 P50406 1/20 0.39
ESRRG P62508 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673990 0.89 ESR1 (0.80) ESR1ALOX15ALOX12KLF10RORC
SCHEMBL726372 0.86 ESR1 (0.83) ESR1ALOX15ALOX12KLF10RORC
SCHEMBL30607257 0.86 ESR1 (0.83) ESR1ALOX15ALOX12KLF10RORC
SCHEMBL19884631 0.86 ESR1 (0.63) ESR1ALOX15ALOX12KLF10RORC
SCHEMBL10719742 0.83 ESR1 (0.59) ESR1ALOX15ALOX12KLF10RORC
SCHEMBL686758 0.82 ESR1 (0.60) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL18494 0.81 ESR1 (0.64) ESR1ALOX15ALOX12KLF10RORC
SCHEMBL2754945 0.80 ESR1 (0.43) ESR1ALOX15ALOX12ESR2HSD17B10
SCHEMBL10127550 0.80 ALOX15 (0.45) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL1416326 0.80 ESR1 (0.71) ESR1ALOX15ALOX12KLF10RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1966279-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD General Electric Company (US) 2008-09-10 EP claimed
WO-2007058779-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD GENERAL ELECTRIC COMPANY (US) 2007-05-24 WO claimed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US claimed
EP-2867275-B1 POLY(PHENYLENE ETHER) PROCESS SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-11-22 EP disclosed
US-8734693-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-05-27 US disclosed
US-8466253-B1 Poly(phenylene ether) process SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-06-18 US disclosed
US-20120277399-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-11-01 US disclosed
US-8075812-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-13 US disclosed
US-8058359-B2 Varnish compositions for electrical insulation and method of using the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-15 US disclosed
US-8053077-B2 Composite-forming method, composites formed thereby, and printed circuit boards incorporating them SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-08 US disclosed
US-20100119716-A1 VARNISH COMPOSITIONS FOR ELECTRICAL INSULATION AND METHOD OF USING THE SAME SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2010-05-13 US disclosed
WO-2008124488-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-10-16 WO disclosed
US-20080246173-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-09 US disclosed
EP-1966279-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD General Electric Company (US) 2008-09-10 EP disclosed
WO-2008094796-A1 COMPOSITE-FORMING METHOD, COMPOSITES FORMED THEREBY, AND PRINTED CIRCUIT BOARDS INCORPORATING THEM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-07 WO disclosed
US-20080178983-A1 COMPOSITE-FORMING METHOD, COMPOSITES FORMED THEREBY, AND PRINTED CIRCUIT BOARDS INCORPORATING THEM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-07-31 US disclosed
US-20080097069-A1 POLY(ARYLENE ETHER) METHOD AND COMPOSITION CITIBANK, N.A., AS COLLATERAL AGENT 2008-04-24 US disclosed
WO-2008048735-A1 POLY (ARYLENE ETHER) AND METHOD FOR PREPARING THEM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-04-24 WO disclosed
WO-2007058779-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD GENERAL ELECTRIC COMPANY (US) 2007-05-24 WO disclosed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US disclosed