Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.82 |
| ▸ | POLB | P06746 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606228 | 0.90 | LMNA (1.00) | LMNAPOLBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6601820 | 0.83 | LMNA (0.58) | LMNAPOLBKMT2AMEN1ACKR3 | |
| SCHEMBL26758003 | 0.77 | LMNA (0.60) | LMNAPOLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11178766 | 0.77 | LMNA (0.73) | LMNAPOLBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11883612 | 0.76 | LMNA (0.51) | LMNAPOLBALDH1A1MAPTDRD2 | |
| Hydrochloric Acid SCHEMBL11794868 | 0.75 | GLA (0.51) | LMNAPOLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6233282 | 0.75 | ALDH1A1 (1.00) | LMNAPOLBALDH1A1SMN1; SMN2GAA | |
| Bromomethane SCHEMBL11879089 | 0.74 | LMNA (0.49) | LMNAPOLBALDH1A1MAPTDRD2 | |
| SCHEMBL14430767 | 0.74 | SLC6A2 (0.70) | RAB9AACKR3DRD2DRD3 | |
| SCHEMBL6607124 | 0.73 | ALDH1A1 (0.56) | LMNAPOLBALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040204417-A1 | Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins | PIERRE FABRE MEDICAMENT (FR) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204417-A1 | Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins | CBR1, CBR3, HCCS | LMNA 2717/4885POLB 4034/4885ALDH1A1 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.