Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 2/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | ICOSLG | O75144 | 3/20 | 0.39 |
| ▸ | ICOS | Q9Y6W8 | 3/20 | 0.39 |
| ▸ | CHUK | O15111 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756672 | 0.89 | HTR2C (0.48) | HDAC3HDAC1HDAC2HDAC6HTR2C | |
| SCHEMBL6754353 | 0.86 | MAPT (0.42) | HTR2CPARP14AURKARPS6KB1ICOSLG | |
| SCHEMBL6756556 | 0.81 | HTR2C (0.71) | HTR2CPARP14 | |
| SCHEMBL6759807 | 0.79 | KMT2A (0.43) | HDAC1HDAC6HTR2CAURKARPS6KB1 | |
| SCHEMBL148468 | 0.74 | ALDH1A1 (0.58) | PARP14KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL6755763 | 0.73 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL6756593 | 0.73 | RAB9A (0.44) | KDM4EAURKARPS6KB1NPC1RAB9A | |
| SCHEMBL148606 | 0.73 | PABPC1 (0.65) | HDAC6KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6754316 | 0.72 | NPC1 (0.45) | HTR2CHSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL149086 | 0.72 | MAPT (0.70) | HDAC6KDM4EHSD17B10RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | H1-2, H1-0, H1-3 | HDAC3 24/4885HDAC1 12/4885HDAC2 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.