Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | FPR1 | P21462 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.49 |
| ▸ | CCNC | P24863 | 2/20 | 0.48 |
| ▸ | CDK8 | P49336 | 2/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.46 |
| ▸ | EED | O75530 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551660 | 1.00 | CASP6 (0.50) | CASP6GFERFPR1FPR2MTNR1A | |
| SCHEMBL3551801 | 1.00 | CASP6 (0.50) | CASP6GFERFPR1FPR2MTNR1A | |
| Hydrochloric Acid SCHEMBL5383077 | 0.98 | FPR1 (0.49) | CASP6GFERFPR1FPR2MTNR1A | |
| Hydrochloric Acid SCHEMBL5406630 | 0.98 | FPR1 (0.49) | CASP6GFERFPR1FPR2MTNR1A | |
| SCHEMBL13724538 | 0.91 | GFER (0.57) | CASP6GFEREEDDRD2DRD3 | |
| SCHEMBL20887685 | 0.88 | ME3 (0.52) | FPR1FPR2MTNR1AMTNR1BCCNC | |
| SCHEMBL3714394 | 0.86 | NAMPT (0.46) | CASP6GFERMTNR1AMTNR1BNAMPT | |
| SCHEMBL27258755 | 0.86 | DRD2 (0.59) | MTNR1AMTNR1BSMPD3DRD2DRD3 | |
| SCHEMBL3551387 | 0.82 | MAPT (0.57) | — | |
| SCHEMBL1749646 | 0.82 | MAPT (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| EP-1748999-A1 | IMIDAZOLO-5-YL-2-ANILINOPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION | AstraZeneca AB (SE) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005075461-A1 | IMIDAZOLO-5-YL-2-ANILINOPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | WO | disclosed |
| EP-1200052-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001068043-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2001-09-20 | — | — | WO | disclosed |